Kidney Health: Key Lab Values for Patients with Kidney Transplants - Internal Medicine

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Please assist the director and colleagues. Thank you! (Forwarded from the director's mailbox)


Hello Director and colleagues,
I would like to inquire about my mother's condition as she is a kidney transplant patient and needs to frequently visit the Chang Gung Urology Department for follow-up.
I would like to understand whether her condition has improved.
Therefore, I have listed the pathology test report (unofficial report) and hope that the Director can provide me with the values, their meanings in Chinese, and their significance:
1.
CLU
2.
BUN (Blood Urea Nitrogen)
3.
CR (Creatinine)
4.
AST (Aspartate Aminotransferase)
5.
NA (Sodium)
6.
K (Potassium)
7.
CRP (C-Reactive Protein)
8.
CK (Creatine Kinase)
9.
LD (Lactate Dehydrogenase)
Could you please let me know which of these values indicate whether my mother's kidney condition is good and within the normal range? Thank you very much for answering my questions.

Zhang, 20~29 year old female. Ask Date: 2003/08/25

Dr. Yang Jun reply Internal Medicine


Hello: In response to your question, your mother is undergoing kidney transplantation due to uremia and requires regular outpatient follow-up and treatment.
Regarding the biochemical tests mentioned in your correspondence, here is an explanation: 1.
GLU: Glucose 2.
BUN: Blood Urea Nitrogen (kidney function test) 3.
CR: Creatinine (kidney function test) 4.
AST: Aspartate Aminotransferase (liver function test) 5.
NA: Sodium (electrolyte) 6.
K: Potassium (electrolyte) 7.
CRP: C-Reactive Protein test (inflammatory response test) 8.
CK: Creatine Kinase 9.
LDH: Lactate Dehydrogenase.
Since the normal reference ranges may vary slightly between laboratories, you may consult Chang Gung Memorial Hospital for their normal values.
To assess whether kidney function is normal, you can refer to the BUN, creatinine, sodium, and potassium levels, and it is best to consult the physician in that specialty for clinical judgment.

Reply Date: 2003/08/25

More Info


Understanding kidney health, especially for patients who have undergone kidney transplants, is crucial for monitoring their recovery and overall well-being. In your mother's case, regular follow-ups and lab tests are essential to assess her kidney function and detect any potential complications early. Below, I will explain the key lab values you mentioned, their meanings, and how they relate to kidney health.

1. GLU (Glucose): This measures the level of glucose in the blood. While not directly related to kidney function, elevated glucose levels can indicate diabetes, which is a significant risk factor for kidney disease.

2. BUN (Blood Urea Nitrogen): This test measures the amount of nitrogen in the blood that comes from urea, a waste product formed in the liver. Normal BUN levels typically range from 7 to 20 mg/dL. Elevated BUN levels can indicate impaired kidney function, dehydration, or excessive protein intake.

3. CR (Creatinine): Creatinine is a waste product generated from muscle metabolism and is filtered out of the blood by the kidneys. Normal levels are generally between 0.6 to 1.2 mg/dL. Elevated creatinine levels can indicate decreased kidney function or damage.

4. AST (Aspartate Aminotransferase): This enzyme is primarily associated with liver function, but it can also be elevated in cases of kidney damage. Normal levels are typically between 10 to 40 units per liter.

5. NA (Sodium): Sodium levels are crucial for maintaining fluid balance in the body. Normal sodium levels range from 135 to 145 mEq/L. Abnormal levels can indicate issues with kidney function, hydration status, or hormonal imbalances.

6. K (Potassium): Potassium is vital for heart and muscle function. Normal potassium levels range from 3.5 to 5.0 mEq/L. Elevated potassium levels (hyperkalemia) can be dangerous and may occur in patients with kidney dysfunction.

7. CRP (C-Reactive Protein): This is a marker of inflammation in the body. Elevated CRP levels can indicate infection or inflammation, which may complicate kidney health.

8. CK (Creatine Kinase): This enzyme is involved in energy production in muscles. Elevated levels can indicate muscle damage, which may indirectly affect kidney function.

9. LD (Lactate Dehydrogenase): This enzyme is released during tissue damage. Elevated levels can indicate various conditions, including hemolysis or liver disease, but are not specific to kidney function.

To assess your mother's kidney health, the most critical values are BUN and creatinine. If these values are within the normal range, it typically indicates that her kidney function is stable. However, it is essential to consider these values in conjunction with clinical symptoms and other tests.
In addition to monitoring these lab values, lifestyle factors such as diet, hydration, and medication adherence play a significant role in kidney health post-transplant. Patients are often advised to follow a low-sodium, low-protein diet and to stay well-hydrated. Regular follow-ups with her healthcare provider will help ensure that any changes in her condition are promptly addressed.

In summary, understanding these lab values and their implications can help you and your family monitor your mother's kidney health effectively. Always consult with her healthcare provider for personalized advice and treatment plans based on her specific health needs.

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