the Side Effects of Sulmatyl on Menstrual Cycle - Psychiatry

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What are the effects of taking Sulmatyl?


I have been taking Sulmatyl 50mg for almost 5 months, one tablet every morning.
This month, my menstrual cycle has been unusual; it has been 12 days and there is still a little bit of bleeding, which has never happened before.
Could this medication have such side effects? Thank you, doctor.

NH, 50~59 year old female. Ask Date: 2022/09/06

Dr. Tang Jiahong reply Psychiatry


Sulpiride can be used to test prolactin levels through a blood draw.
If the concentration is high, it indicates hyperprolactinemia, which may affect menstruation.
However, it is also possible that this is not the sole reason.
It is recommended to consult a gynecologist for a comprehensive evaluation and examination.

Reply Date: 2022/09/06

More Info


Sulmatyl, known generically as sulpiride, is an atypical antipsychotic medication primarily used to treat conditions such as schizophrenia and depression. It can also be prescribed for anxiety disorders and other related conditions. While the medication is effective for its intended uses, it is essential to understand its potential side effects, especially concerning the menstrual cycle.

One of the known side effects of sulpiride is its influence on hormonal balance, particularly through its action on dopamine receptors. Sulpiride can increase prolactin levels in the body, which may lead to various reproductive issues, including menstrual irregularities. Elevated prolactin levels can cause symptoms such as galactorrhea (the production of breast milk in individuals who are not breastfeeding), amenorrhea (the absence of menstruation), or irregular menstrual cycles.
In your case, experiencing prolonged menstrual bleeding for twelve days could be attributed to the effects of sulpiride on your hormonal balance. While it is not uncommon for medications to cause changes in menstrual patterns, it is crucial to differentiate between normal variations and those that may indicate a more serious issue.
If you have been taking sulpiride consistently for five months and have noticed this unusual change in your menstrual cycle, it is advisable to consult with your healthcare provider. They can evaluate your symptoms in the context of your overall health and medication regimen. They may also consider checking your prolactin levels and assessing whether the current dosage of sulpiride is appropriate for you or if an alternative treatment might be more suitable.

Additionally, it is important to consider other factors that could contribute to changes in your menstrual cycle, such as stress, changes in weight, other medications, or underlying health conditions. Your healthcare provider can help you explore these possibilities and determine the best course of action.

In summary, while sulpiride can potentially affect your menstrual cycle due to its influence on prolactin levels, it is essential to discuss any significant changes with your healthcare provider. They can provide personalized advice and ensure that your treatment plan remains effective and safe. Always remember that any new or unusual symptoms should be reported to a healthcare professional to rule out any serious underlying conditions.

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