Abnormal Kidney Function: High Creatinine and Uric Acid Levels

Renal dysfunction

Hello doctor, I am currently eighteen years old.
In my health examination report, I found that my creatinine level is elevated (1.45) and my uric acid level is high (9.2).
Additionally, there is protein in my urine.
Could you please explain what issues this might indicate? Do I need further testing, or is it okay to leave it as is?

A-Song, 10~19 year old female. Ask Date: 2022/09/24

Dr. Hong Yuanbin reply Internal Medicine

Hello, based on your description, it is likely that you have nephrotic syndrome.
Given your age, most cases are benign conditions.
I recommend visiting a nephrology clinic for further confirmation and examination.
Thank you for your inquiry.

Reply Date: 2022/09/24

More Info

High levels of creatinine and uric acid, along with the presence of protein in urine, can indicate potential issues with kidney function and overall health. Let's break down what these findings might mean and the steps you should consider taking.

Understanding Creatinine and Uric Acid Levels
1. Creatinine: This is a waste product produced by muscle metabolism and is usually filtered out of the blood by the kidneys. A normal creatinine level typically ranges from about 0.6 to 1.2 mg/dL for adults, but this can vary based on muscle mass, age, and sex. Your level of 1.45 mg/dL is elevated, suggesting that your kidneys may not be filtering waste effectively.

2. Uric Acid: This is another waste product, formed from the breakdown of purines found in certain foods and drinks. Normal levels of uric acid are generally between 3.5 and 7.2 mg/dL for men, and slightly lower for women. A level of 9.2 mg/dL is significantly high and can lead to conditions such as gout, which is characterized by painful inflammation in the joints.

3. Protein in Urine: The presence of protein in urine (proteinuria) can indicate kidney damage or disease. Normally, urine should contain little to no protein. The kidneys filter blood, and when they are damaged, they may allow protein to leak into the urine.

Possible Causes
The combination of high creatinine, high uric acid, and protein in urine can be indicative of several conditions:
- Kidney Disease: Chronic kidney disease (CKD) or acute kidney injury (AKI) can lead to elevated creatinine levels. The kidneys may struggle to filter waste effectively, leading to an accumulation of creatinine in the blood.

- Dehydration: Insufficient fluid intake can concentrate waste products in the blood, leading to elevated creatinine and uric acid levels.

- Diet: A diet high in protein or purines (found in red meat, seafood, and alcohol) can raise uric acid levels.
- Genetic Factors: Some individuals may have a genetic predisposition to higher uric acid levels or kidney issues.

- Other Medical Conditions: Conditions such as hypertension, diabetes, or autoimmune diseases can also affect kidney function and lead to these abnormalities.

Next Steps
Given your age and the concerning nature of these results, it is crucial to take the following steps:
1. Consult a Nephrologist: A kidney specialist can provide a thorough evaluation of your kidney function and determine the underlying cause of your elevated levels. They may recommend additional tests, such as a 24-hour urine collection, imaging studies, or a kidney biopsy, depending on your situation.

2. Lifestyle Modifications: While waiting for your appointment, consider making some lifestyle changes:
- Hydration: Ensure you are drinking enough water to help your kidneys function properly.

- Diet: Limit foods high in purines (like red meat and shellfish) and reduce salt intake. A balanced diet can help manage uric acid levels.

- Avoid Alcohol: Alcohol can increase uric acid levels and put additional strain on your kidneys.

3. Monitor Symptoms: Keep track of any symptoms you may experience, such as swelling, changes in urination, or joint pain, and report these to your healthcare provider.

4. Regular Follow-ups: Regular monitoring of your kidney function through blood and urine tests is essential to assess any changes and the effectiveness of any interventions.

Conclusion
In summary, elevated creatinine and uric acid levels, along with protein in urine, warrant further investigation to determine the underlying cause and appropriate management. Early detection and intervention can significantly improve outcomes, especially in young individuals like yourself. It is essential to consult with a healthcare professional promptly to address these concerns and develop a suitable plan for your health.

Similar Q&A

Understanding Abnormal Kidney Function Tests: Causes and Next Steps

The health examination report indicates elevated creatinine levels (1.45 mg/dL) and high uric acid levels (9.2 mg/dL), along with the presence of protein in the urine. Should I undergo further testing? What could be the causes of these abnormalities?

Dr. Huang Yaoxuan reply Internal Medicine
Hello, Asong: It is recommended that you consult a nephrology outpatient clinic to monitor the elevated creatinine levels and protein in your urine. For high uric acid levels, you may follow up with a rheumatology outpatient clinic. Thank you!

Understanding High Creatinine and Uric Acid Levels: What You Need to Know

Hello doctor, I found out during a health check at school that my kidney function test shows a creatinine level of 1.8 mg/dL and a uric acid level of 8 mg/dL. What diseases could this indicate, and how should I manage it? Thank you.

Dr. Yang Jun reply Internal Medicine
Hello: In response to your inquiry, the kidney function test indicated a serum creatinine level of 1.8 mg/dL, which exceeds the normal range, suggesting impaired kidney function and the possibility of renal failure. Given your age, the elevated creatinine level may indicate acute...

Understanding Abnormal Kidney Function: High Creatinine and Protein in Urine

Hello doctor, I am currently 18 years old, 170 cm tall, and weigh 47 kg. During a health check-up, it was found that my creatinine level is elevated (1.45) and my uric acid level is high (9.2). Additionally, there is protein in my urine. Is this related to kidney function or is i...

Dr. Jian Weihong reply Urology
Hello: It is advisable to test multiple times. Be cautious with elevated creatinine and uric acid levels; pay attention to your health. To lower uric acid, focus on diet and hydration. Wishing you good health.

Understanding Elevated Creatinine Levels: Causes and Concerns

Hello, doctor. This year, during my health check-up, my kidney function test showed a creatinine level of 1.5 and a uric acid level of 4.31. Last year, my creatinine level was 1.4 and my uric acid level was 5.3. My BMI has been 22 for both years. I have a regular exercise routine...

Dr. Wu Hongjie reply Internal Medicine
Hello, regarding your elevated creatinine levels, it is recommended that you see a nephrologist for further examination and follow-up. Since your uric acid levels are normal, the cause of the renal dysfunction may require additional urine tests and blood tests to determine whethe...