Pap Smear Results: Frequency and HPV Testing Explained - Obstetrics and Gynecology

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What are the results of the Pap smear test?


Hello Doctor, I had a follow-up appointment two months after my cesarean section, during which I also had a Pap smear.
During the internal examination, the doctor mentioned that I had a bit of increased discharge and performed a bacterial culture.
Additionally, I had an HPV test done.
The results showed that my Pap smear was classified as ASC-US (Atypical Squamous Cells of Undetermined Significance), the bacterial culture was negative, and the HPV test was also negative.
The doctor advised that due to the traditional interpretation of Pap smears, this result can occur, and since my HPV test was negative, I don't need to worry about it.
I was instructed to remember to have a Pap smear every year.

I would like to ask if it is indeed sufficient to have a Pap smear once a year? I found online that many people have similar experiences; some are monitored, while others also have HPV tests, leading to annual Pap smears.
I typically have an HPV test every 5 to 6 years, and my husband is my only sexual partner since we are high school sweethearts.
Given this, if my next Pap smear is scheduled for a year from now, should I also have an HPV test done? Thank you.

Wendy, 30~39 year old female. Ask Date: 2022/11/29

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, due to the ASCUS result from your Pap smear, I recommend that you have a follow-up Pap smear in three months.
Wishing you good health.

Reply Date: 2022/11/29

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Understanding Pap Smear Results: Frequency and HPV Testing Explained
It's great that you're taking an active role in your health by asking questions about your Pap smear results and HPV testing. Let's break down your concerns regarding the frequency of Pap smears, the implications of your results, and the role of HPV testing.

First, it’s important to understand what a Pap smear is. A Pap smear, or Pap test, is a screening procedure for cervical cancer that involves collecting cells from your cervix to detect any abnormalities. The results are often categorized into different classes, with "ASC-US" (Atypical Squamous Cells of Undetermined Significance) indicating that some cells appear abnormal, but it’s unclear if they are pre-cancerous. A result of "4" typically indicates a higher level of concern, often leading to further investigation, such as colposcopy or HPV testing.

In your case, the Pap smear result of ASC-US, combined with a negative HPV test, is reassuring. The negative HPV test suggests that you do not have a high-risk strain of the virus that could lead to cervical cancer. Your doctor’s recommendation to continue with annual Pap smears is consistent with guidelines for women in your age group and health status. The general recommendation is that women aged 21 to 29 should have a Pap test every three years, while women aged 30 to 65 can have Pap tests combined with HPV testing every five years or Pap tests alone every three years.

Regarding your question about the necessity of HPV testing, since you have a history of negative HPV results and are in a monogamous relationship, your risk of developing cervical cancer is lower. However, it is still advisable to follow your healthcare provider's recommendations. If your next Pap smear is normal, you may not need to have HPV testing every year, especially if you have consistently negative results. The decision to include HPV testing in your next screening can depend on your age, health history, and the specific guidelines your healthcare provider follows.

It's also worth noting that while HPV can remain dormant for years, regular screenings are crucial for early detection of any changes in cervical cells. If you experience any unusual symptoms, such as abnormal bleeding or pelvic pain, you should consult your healthcare provider sooner than your scheduled appointment.

In summary, based on your current health status and the results of your tests, continuing with annual Pap smears is a prudent approach. You may not need to add HPV testing every year, especially if your results remain negative. However, always discuss your concerns and preferences with your healthcare provider to tailor a screening schedule that best suits your individual health needs.

Remember, maintaining open communication with your healthcare provider and staying informed about your health is key to effective preventive care. Regular screenings, along with awareness of any changes in your body, will help ensure your continued health and well-being.

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