Long-Term Effects of Daily Chitosan and Brewer's Yeast on Kidney and Liver Health - Nutrition

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Brewer's yeast and chitosan?


Is there any long-term impact on the body, such as kidney or liver function, from daily consumption of chitosan and brewer's yeast?

kellie, 20~29 year old female. Ask Date: 2003/11/13

Dr. Shi Guimei reply Nutrition


Hello! Brewer's yeast, marketed for health benefits, is no longer a fermenting yeast but rather an aged yeast.
Many research reports indicate that true brewer's yeast has high nutritional value (many products on the market are not true brewer's yeast, and commercially available nutritional yeast is typically inactive), with a significant proportion of protein.
Therefore, if your regular dietary protein intake is sufficient, or if certain organ functions (such as the kidneys or liver) are impaired, it is essential to carefully estimate your intake.
Chitin is a type of polysaccharide and a high molecular weight carbohydrate, and there has been a recent surge in the popularity of chitosan.
However, there are currently almost no reports on the long-term health effects of its consumption.
This is respectfully submitted by Dietitian Shih Kuei-Mei, Director of the Nutrition Department at Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2003/11/13

More Info


When considering the long-term effects of daily supplementation with chitosan and brewer's yeast on kidney and liver health, it is essential to understand the properties and metabolic pathways of these substances.

Chitosan is a biopolymer derived from chitin, which is found in the shells of crustaceans. It is often marketed as a weight-loss supplement due to its ability to bind fats and reduce their absorption in the intestines. Chitosan is not significantly absorbed in the gastrointestinal tract, which means it primarily acts locally in the gut. However, its long-term consumption can lead to gastrointestinal side effects such as bloating, constipation, or diarrhea in some individuals.
From a renal perspective, chitosan is generally considered safe for the kidneys. There is limited evidence suggesting that it could affect kidney function adversely, especially in individuals with pre-existing kidney conditions. However, it is crucial to maintain adequate hydration while taking chitosan, as it can absorb water and potentially lead to dehydration if fluid intake is not sufficient.

Brewer's yeast, on the other hand, is a rich source of B vitamins, proteins, and minerals. It is often used as a nutritional supplement to improve energy levels, support metabolism, and enhance immune function. Brewer's yeast is generally well-tolerated and is not known to have significant adverse effects on liver or kidney function in healthy individuals. However, individuals with certain conditions, such as gout or those who are sensitive to yeast, may experience adverse reactions.

In terms of liver health, brewer's yeast has been studied for its potential benefits. Some studies suggest that it may help improve liver function due to its high content of B vitamins and antioxidants. However, excessive consumption could lead to an overload of certain nutrients, which might stress the liver over time, especially in individuals with pre-existing liver conditions.

Potential Risks and Recommendations:
1. Kidney Function: While both chitosan and brewer's yeast are generally safe for the kidneys, individuals with existing kidney issues should consult a healthcare provider before starting any new supplement regimen. Regular monitoring of kidney function through blood tests (such as serum creatinine and eGFR) is advisable for those on long-term supplementation.

2. Liver Function: For liver health, it is essential to consider the overall diet and lifestyle. While brewer's yeast may offer some benefits, it should not replace a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Individuals with liver disease or elevated liver enzymes should also seek medical advice before taking brewer's yeast.

3. Hydration: Adequate hydration is crucial when taking chitosan to prevent potential gastrointestinal issues and support kidney function.

4. Consultation with Healthcare Providers: Before starting any long-term supplementation, especially if you have pre-existing health conditions or are taking other medications, it is vital to consult with a healthcare provider. They can provide personalized advice based on your health status and nutritional needs.

In summary, while chitosan and brewer's yeast are generally considered safe for long-term use in healthy individuals, it is essential to monitor your health and consult with healthcare professionals to ensure that these supplements do not adversely affect your kidney or liver function. Regular health check-ups and blood tests can help in early detection of any potential issues, allowing for timely intervention if necessary.

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