Recommended Supplements for HER2+ Cancer Patients Under Targeted Therapy

My mother is HER2 positive and is currently undergoing targeted therapy. What supplements can she take?

Hello Doctor,
I was advised by other physicians to consult a hematologist-oncologist.
I would like to ask about my mother, who is 56 years old and was diagnosed with HER2-positive breast cancer last year.
She has completed chemotherapy and is currently undergoing targeted therapy.
I would like to know if she can take liver health supplements like vitamin B complex or natto-derived red yeast rice to reduce fatty liver.
Is it true that brown seaweed extract can inhibit cancer cells? Could you also recommend any dietary supplements that could be beneficial during her targeted therapy? Thank you, Doctor.

Zhang Hongyi, 30~39 year old female. Ask Date: 2023/04/17

Dr. Hu Ziren reply Oncology

1.
To reduce fatty liver, exercise and dietary control are essential; however, taking liver health supplements such as vitamin B complex or natto red yeast rice may be beneficial.
2.
The use of brown rice suppressants is not recommended.
3.
During targeted therapy for breast cancer, there are no dietary restrictions; it is advised to maintain a normal diet, continue exercising, and attend regular follow-up appointments.

Reply Date: 2023/04/17

More Info

When it comes to managing health during targeted therapy for HER2-positive breast cancer, it is essential to approach the use of supplements and dietary changes with caution and informed guidance. Your mother’s situation, having completed chemotherapy and currently undergoing targeted therapy, requires careful consideration of any additional supplements or dietary modifications.

Supplements and Nutritional Support
1. Vitamin B Complex and Liver Health: Taking a vitamin B complex can be beneficial, especially for energy metabolism and overall health. However, it is crucial to ensure that any supplement taken does not interfere with the ongoing cancer treatment. The liver is a vital organ for metabolizing medications, and while vitamin B can support liver function, it is essential to consult with her oncologist or a nutritionist before starting any new supplement.

2. Natto and Red Yeast Rice: Natto, which contains a substance called nattokinase, may have some health benefits, including potential cardiovascular benefits. Red yeast rice is known for its cholesterol-lowering effects. While these may be helpful for general health, their effects on cancer treatment are not well-established. Therefore, it is advisable to discuss these options with her healthcare provider to ensure they are safe and appropriate for her specific condition.

3. Brown Seaweed Extract (褐抑錠): There are claims that brown seaweed extract can inhibit cancer cell growth, but scientific evidence supporting these claims is limited. It is crucial to approach such supplements with skepticism and to prioritize treatments that have been clinically validated. Again, consulting with her oncologist is vital before introducing any new supplement.

General Dietary Recommendations
During targeted therapy, maintaining a balanced diet rich in whole foods is essential. Here are some general dietary recommendations:
- Fruits and Vegetables: A diet high in fruits and vegetables can provide essential vitamins, minerals, and antioxidants that support overall health and may help the body cope with the side effects of cancer treatment.

- Lean Proteins: Incorporating lean proteins such as chicken, fish, legumes, and tofu can help maintain muscle mass and support recovery.

- Healthy Fats: Sources of healthy fats, such as avocados, nuts, seeds, and olive oil, can provide energy and support overall health.

- Hydration: Staying well-hydrated is crucial, especially if there are side effects from treatment that may lead to dehydration.

Monitoring and Follow-Up
Regular follow-ups with her healthcare team are essential to monitor her response to treatment and any potential side effects. It is also an opportunity to discuss any supplements she is considering. The healthcare team can provide personalized advice based on her overall health, treatment plan, and any other medications she may be taking.

Conclusion
In summary, while some supplements may offer health benefits, it is crucial to approach them with caution during targeted therapy for HER2-positive breast cancer. Consulting with healthcare professionals, including oncologists and nutritionists, will ensure that any supplements taken are safe and beneficial for her specific situation. A balanced diet, regular monitoring, and open communication with her healthcare team will provide the best support for her health during this challenging time.

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