Iron Supplementation and Its Effects on Health - Family Medicine

Share to:

Medication adherence issues


Hello, doctor.
During my company health check-up on December 7, 2021, my blood test results showed a white blood cell count of 7.7, red blood cell count of 4.19, hemoglobin of 10, hematocrit of 31.4, mean corpuscular hemoglobin of 23.9, and mean corpuscular volume of 74.8.
Last year, I visited a clinic on September 9, 2022, where the doctor performed a blood test, revealing a white blood cell count of 8.1, red blood cell count of 4.32, hemoglobin of 10.7, hematocrit of 32.7, mean corpuscular hemoglobin of 24.7, mean corpuscular volume of 75.7, and ferritin of 11.2.
The doctor diagnosed me with iron deficiency and prescribed iron supplements.
However, I did not pay attention to the contraindications of taking iron supplements (which should not be taken with tea, coffee, or milk) and have been taking them for almost a year.
By the end of April 2023, I noticed a light purple discoloration at the base of my fingers.
I consulted a doctor on May 8, 2023, who also conducted a blood test, showing a white blood cell count of 8.5, red blood cell count of 4.54, hemoglobin of 12.6, hematocrit of 38.6, mean corpuscular hemoglobin of 27.7, and mean corpuscular volume of 85.
The doctor indicated that my blood values were normal and recommended that I see a rheumatologist.
I have some questions for the doctor: 1.
Could the contraindications of iron supplements potentially cause the light purple discoloration at the base of my fingers? 2.
Why was I advised to see a rheumatologist? 3.
What other specialties would the doctor recommend I consult?

Yi, 30~39 year old female. Ask Date: 2023/05/23

Dr. Ye Qianyu reply Family Medicine


Hello! 1.
The contraindications for taking iron supplements can affect iron absorption; your serum ferritin levels are quite low, so there should be no issue with iron deposition.
2.
In some rheumatologic and autoimmune diseases, fingers may change to purple or white when the weather gets colder.
3.
It is recommended that you visit a family medicine clinic for further evaluation, and if necessary, a referral can be made.

Reply Date: 2023/05/23

More Info


When considering iron supplementation, it is essential to understand the various factors that influence its effectiveness and potential side effects. Iron is a crucial mineral for the body, primarily involved in the production of hemoglobin, which carries oxygen in the blood. However, the choice of iron supplement, dosage, and timing can significantly affect how well it works and how your body tolerates it.


1. Choosing the Right Iron Supplement
There are two primary forms of iron supplements: ferrous (Fe2+) and ferric (Fe3+). Ferrous iron is generally better absorbed by the body, but it can cause gastrointestinal discomfort, including nausea, constipation, and diarrhea. On the other hand, ferric iron is less likely to cause these side effects but is also less efficiently absorbed. If you have experienced discomfort with ferrous iron, you might consider switching to a ferric form or starting with a lower dose of ferrous iron and gradually increasing it.

In your case, you mentioned taking a supplement that contains 40mg of iron and another with 100mg. It’s important to note that higher doses can lead to increased side effects. If you are considering a higher dose, it is advisable to monitor your body's response closely. Additionally, taking iron supplements with vitamin C can enhance absorption, while consuming them with dairy products, coffee, or tea can inhibit absorption.


2. Potential Side Effects and Monitoring
Common side effects of iron supplementation include dark stools, nausea, and abdominal discomfort. If you experience persistent nausea or other gastrointestinal issues, it may be beneficial to take the supplement with food, despite the potential decrease in absorption. If you notice any unusual symptoms, such as the purple discoloration at the base of your fingers, it is crucial to consult a healthcare professional. While this discoloration is unlikely to be directly caused by iron supplementation, it could indicate other underlying issues that need to be addressed.


3. Consulting Specialists
Given your history of iron deficiency anemia and the recent symptoms, your doctor’s recommendation to see a rheumatologist may be due to concerns about autoimmune conditions or other systemic issues that could be affecting your blood and overall health. Rheumatologists specialize in conditions that affect the joints and connective tissues, which can sometimes present with symptoms like discoloration or changes in circulation.

In addition to a rheumatologist, you might also consider consulting a hematologist, who specializes in blood disorders. They can provide a more in-depth analysis of your blood work and help determine if there are any underlying conditions contributing to your symptoms.


4. Importance of Regular Monitoring
Regular blood tests are essential to monitor your hemoglobin levels, ferritin (iron stores), and overall blood health. Since you have been on iron supplementation for an extended period, it is crucial to ensure that your iron levels are within the normal range and that you are not experiencing iron overload, which can lead to serious health issues.


Conclusion
In summary, when choosing an iron supplement, consider the type of iron, dosage, and potential interactions with food and other medications. Monitor your body’s response closely, and do not hesitate to seek medical advice if you experience unusual symptoms. Regular follow-ups with your healthcare provider are vital to ensure that your treatment is effective and to rule out any other health concerns. If your symptoms persist or worsen, further evaluation by a specialist may be warranted to ensure comprehensive care.

Similar Q&A

Understanding Iron Supplementation in Managing Iron Deficiency Anemia

On August 23, the blood test report showed Hb: 9.9, MCV: 68.9, serum iron: 14, and ferritin: 1.21, indicating iron deficiency anemia. After taking iron supplements (ferrous gluconate) for about one and a half months, a follow-up blood test on October 15 revealed Hb: 10.1, MCV: 71...


Dr. Lin Zhebin reply Family Medicine
Hello: In addition to iron supplementation for iron deficiency anemia, it is important to identify the underlying cause of chronic blood loss that may be contributing to the anemia. Given your age, a common cause could be heavy menstrual bleeding. Generally, iron supplementation ...

[Read More] Understanding Iron Supplementation in Managing Iron Deficiency Anemia


Understanding Iron Deficiency: Symptoms, Nutrition, and Dietary Sources

Hello, I have recently started experiencing some symptoms of anemia. Could it be due to iron deficiency, or could there be other factors involved? I would also like to know what nutritional content iron has, considering it is a trace element. What types of foods should I consume ...


Dr. Shi Guimei reply Nutrition
Hello! There are many causes of anemia. It is advisable to seek medical evaluation first. If it is confirmed to be iron deficiency anemia, relying solely on diet may not provide sufficient iron. A physician should assess whether iron supplementation is necessary. In terms of diet...

[Read More] Understanding Iron Deficiency: Symptoms, Nutrition, and Dietary Sources


Understanding High-Dose Iron Supplements: Benefits and Precautions

I previously had anemia and took iron prescribed by my doctor, but after finishing the treatment, I didn't return for follow-up visits. Occasionally, when I felt unwell, I would buy over-the-counter iron supplements and took them intermittently to avoid side effects. Recentl...


Dr. Hou Fangmin reply Pharmacology
Hello: 1. The iron supplement you mentioned is ferrous iron. When comparing ferrous (Fe²⁺) and ferric (Fe³⁺) iron, ferrous iron has better absorption but a higher likelihood of causing gastrointestinal discomfort, and it is more affected by food (co-administration with food can...

[Read More] Understanding High-Dose Iron Supplements: Benefits and Precautions


Foods to Lower High Iron Levels in Your Blood

What foods can help improve high iron levels in the blood?


Dr. Tang Weili reply Nutrition
Dear Yiya, Hello, has your doctor informed you about the reasons for your elevated iron levels? Is it possible to improve this through physiological metabolism? Currently, you should avoid consuming processed foods that claim to be high in iron, such as iron-fortified milk powde...

[Read More] Foods to Lower High Iron Levels in Your Blood


Related FAQ

Anemia

(Family Medicine)

Health Supplements

(Family Medicine)

Family Medicine

(Nutrition)

Vitamins

(Family Medicine)

Heavy Metal Poisoning

(Family Medicine)

Health Check-Up Report

(Family Medicine)

Anemia

(Nutrition)

Blood Pressure

(Family Medicine)

Blood Test

(Family Medicine)

Hemoglobin A1C

(Family Medicine)