Managing Drug Allergies and Side Effects in Cardiovascular Patients - Cardiology

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Drug allergy?


I had carotid artery stents placed on both sides in September of last year and January of this year.
I am currently taking antihypertensive medication, lipid-lowering medication, and dual antiplatelet therapy.
The problem is that after taking dual antiplatelet therapy for 5.5 months, especially with clopidogrel, it has been very painful and frustrating for me.
Besides feeling uncomfortable, I developed ulcers and polyps after an endoscopy, and my throat was red and swollen after a laryngoscopy.
Other physicians have advised me to discuss changing medications with my doctor, but he responded that clopidogrel is the best option.
Is this true? How can I address the issue of taking medication without harming my physical and mental well-being?

Chen Weihao, 50~59 year old female. Ask Date: 2024/02/17

Dr. Cai Guiqin reply Cardiology


I recommend that you: 1.
Discuss the above situation further with your attending physician.
2.
Consider consulting a cardiologist at a major hospital.
Wishing you good health.
Thank you!

Reply Date: 2024/02/17

More Info


Managing drug allergies and side effects in cardiovascular patients is a critical aspect of patient care, especially for those who have undergone procedures such as carotid artery stenting. It is not uncommon for patients to experience adverse effects from medications, particularly those prescribed for managing cardiovascular conditions, such as hypertension, hyperlipidemia, and antiplatelet therapy.

In your case, you mentioned experiencing significant discomfort while taking Bokey (which contains the active ingredient Aspirin) as part of your dual antiplatelet therapy. Aspirin is widely used to prevent thrombotic events in patients with a history of cardiovascular disease, but it can lead to gastrointestinal issues, including ulcers and gastritis, which may explain the symptoms you are experiencing, such as ulcers and throat swelling.

The first step in addressing your concerns is to have an open and honest discussion with your healthcare provider. It is essential to communicate the severity of your symptoms and how they are impacting your quality of life. While your doctor may believe that Aspirin is the best option for your condition, it is crucial to explore alternatives if the side effects are intolerable. There are other antiplatelet medications available, such as Clopidogrel (Plavix) or Ticagrelor, which may be better tolerated by some patients. Your doctor can help determine if switching to a different medication is appropriate based on your medical history and current health status.

In addition to discussing medication alternatives, there are several strategies you can employ to manage side effects and improve your overall well-being:
1. Medication Timing and Food Intake: Taking medications with food can sometimes help mitigate gastrointestinal side effects. If you are not already doing so, consider taking your medications with a meal or snack to see if it alleviates some discomfort.

2. Use of Gastroprotective Agents: If you are experiencing gastrointestinal issues, your doctor may recommend the use of proton pump inhibitors (PPIs) or H2 blockers to help protect your stomach lining while you continue your antiplatelet therapy. These medications can reduce the risk of ulcers and help manage symptoms.

3. Regular Monitoring: Regular follow-ups with your healthcare provider are essential to monitor your response to medications and any side effects. This allows for timely adjustments to your treatment plan as needed.

4. Lifestyle Modifications: Incorporating lifestyle changes such as a balanced diet, regular exercise, and stress management techniques can improve your overall health and may help mitigate some side effects of medications.

5. Seeking a Second Opinion: If you feel that your concerns are not being adequately addressed, consider seeking a second opinion from another cardiologist or a specialist in cardiovascular medicine. They may provide additional insights or alternative treatment options.

6. Patient Education: Understanding your medications, their purpose, and potential side effects can empower you to make informed decisions about your treatment. Ask your healthcare provider for educational resources or materials that can help you better understand your condition and medications.

In conclusion, managing drug allergies and side effects in cardiovascular patients requires a collaborative approach between the patient and healthcare provider. Open communication about your symptoms, exploring alternative medications, and implementing supportive strategies can significantly enhance your treatment experience and overall quality of life. Remember, your comfort and well-being are paramount, and it is essential to advocate for your health needs.

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