Persistent Acne: Causes and Treatment Risks - Dermatology

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Annoying acne?


Hello Doctor: I have been suffering from acne for twenty years now.
The affected areas include not only my face, neck, chest, and back, but sometimes also my buttocks.
I have consulted numerous traditional Chinese medicine practitioners and dermatologists without finding a permanent solution.
I have a few questions I would like to ask for your assistance, thank you.

1.
Why do I still continue to have acne at over 30 years old?
2.
Does long-term use of antibiotics for acne treatment harm the function of organs such as the liver and kidneys? Will it lead to antibiotic resistance in my body?

F Jun, 30~39 year old female. Ask Date: 2004/11/11

Dr. Jiang Zheen reply Dermatology


In your case, oral isotretinoin should be more effective.
You can apply for this medication at a teaching hospital.
As for why it has persisted for so long, it is likely related to your constitution and lifestyle habits.
Some antibiotics can indeed lead to the development of antibiotic-resistant bacteria.
Wishing you well.

Reply Date: 2004/11/11

More Info


Persistent acne can be a frustrating and distressing condition, especially when it has lasted for two decades as you described. Understanding the underlying causes and the potential risks associated with treatment is crucial for managing this condition effectively.

1. Why Am I Still Experiencing Acne in My 30s?
Acne is often associated with adolescence due to hormonal changes, but it can persist into adulthood for various reasons. Hormonal fluctuations, particularly related to androgens (male hormones that are present in both men and women), can lead to increased oil production in the skin, which can clog pores and result in acne. Conditions such as polycystic ovary syndrome (PCOS) in women can also contribute to persistent acne due to hormonal imbalances.

Other factors that may contribute to adult acne include:
- Diet: High glycemic index foods and dairy products have been linked to acne in some studies.

- Stress: Stress can exacerbate acne by increasing hormone levels that stimulate oil production.

- Skin Care Products: Some products may clog pores or irritate the skin, leading to breakouts.

- Genetics: A family history of acne can increase the likelihood of experiencing it yourself.

It’s essential to consult with a dermatologist who can evaluate your specific situation, possibly conduct hormone level tests, and recommend appropriate treatments tailored to your needs.

2. Risks of Long-term Antibiotic Use for Acne Treatment
Long-term use of antibiotics for acne treatment can indeed pose risks to your health. Here are some considerations:
- Liver and Kidney Function: While most topical and oral antibiotics used for acne are generally safe when prescribed by a healthcare provider, prolonged use can potentially affect liver and kidney function. Regular monitoring through blood tests is advisable to ensure these organs are functioning properly.


- Antibiotic Resistance: One of the significant concerns with long-term antibiotic use is the development of antibiotic resistance. This occurs when bacteria evolve and become resistant to the effects of medications, making future infections harder to treat. This is particularly concerning if antibiotics are used for extended periods without breaks.

- Gut Health: Antibiotics can disrupt the balance of good bacteria in your gut, leading to gastrointestinal issues and potentially affecting your overall health. Probiotics may help mitigate some of these effects, but it’s best to discuss this with your healthcare provider.

- Alternative Treatments: If you are concerned about the risks associated with long-term antibiotic use, there are alternative treatments available for acne, including topical retinoids, hormonal treatments (like birth control pills for women), and isotretinoin for severe cases. Each of these options has its own set of benefits and risks, which should be discussed with your dermatologist.

In conclusion, persistent acne can be influenced by various factors, and it is essential to work closely with a healthcare provider to identify the underlying causes and develop a comprehensive treatment plan. Regular follow-ups and open communication about your concerns regarding treatment risks are vital for managing your condition effectively. Remember, you are not alone in this journey, and there are effective strategies to help you achieve clearer skin.

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