Medication Side Effects: Are You Sick or Just Adjusting? - Pharmacology

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Is it hard to tell if I'm sick?


Doctor: I am currently being treated for depression.
The doctor just switched my medication and added a new one...
I am currently taking: Wellbutrin 150 mg (just switched medications less than a week ago) and Stilnox 20 mg (increased from one tablet to two).
It's been about two to three days since the medication change...
However, I have been experiencing fatigue, dizziness, photophobia, and a vacant stare.
I feel extremely tired and somewhat unbalanced...
Since I am unable to return for a follow-up appointment in the near future, and these symptoms are very distressing, I am unsure if they are side effects of the medication or if I am becoming ill???

You Mei Mei, 10~19 year old female. Ask Date: 2005/04/26

Dr. Hou Fangmin reply Pharmacology


Hello; I understand your anxiety.
Wellbutrin is used to treat depression and nicotine dependence, and it can also serve as an aid for smoking cessation.
Its side effects can vary from person to person and may include chest pain, weakness, dizziness, dry mouth, nausea, and vomiting.
On the other hand, there are sleeping medications that can cause residual drowsiness and dizziness for some individuals, but many people do not experience these symptoms.
If you are experiencing side effects or discomfort, please discuss this with your physician, as they will have the best understanding of your situation and can adjust your dosage accordingly.
Does this answer your question? Bye.

Reply Date: 2005/04/26

More Info


When dealing with medication for depression, particularly when changes are made to your regimen, it is crucial to understand the potential side effects and how they may impact your daily life. In your case, you mentioned experiencing fatigue, dizziness, light sensitivity, and a sense of imbalance after recently adjusting your medication. These symptoms can indeed be side effects of the medications you are taking, particularly Wellbutrin (bupropion) and Stilnox (zolpidem).

Understanding Medication Side Effects:
1. Wellbutrin (Bupropion): This medication is commonly used to treat depression and can also aid in smoking cessation. While it is generally well-tolerated, some individuals may experience side effects such as insomnia, dry mouth, dizziness, and increased anxiety. The adjustment period after changing the dosage or switching medications can lead to temporary side effects as your body acclimates to the new chemical balance.

2. Stilnox (Zolpidem): This medication is a sedative primarily used for the short-term treatment of insomnia. Increasing the dosage from one to two pills can lead to heightened sedation, dizziness, and cognitive impairment, especially if your body is not accustomed to the higher dose. Side effects can include drowsiness, confusion, and a sense of imbalance, which you are experiencing.

3. Adjustment Period: It is essential to recognize that when medications are changed or dosages are adjusted, your body may require time to adapt. During this period, side effects can manifest as your system adjusts to the new medication levels. This adjustment can take several days to weeks, depending on the individual and the specific medications involved.

4. Distinguishing Between Side Effects and Symptoms of Illness: It can be challenging to differentiate between side effects of medication and symptoms of the underlying condition (in this case, depression). If the symptoms you are experiencing are new and coincide with the medication change, they are likely side effects. However, if these symptoms persist beyond the adjustment period or worsen, it is crucial to consult your healthcare provider.

5. What to Do Next: Since you mentioned that you cannot return for a follow-up appointment soon, consider reaching out to your healthcare provider via phone or secure messaging if available. They can provide guidance on whether to continue with the current regimen or if adjustments are necessary. It is essential not to stop or alter your medication without professional advice, as this can lead to withdrawal symptoms or a worsening of your condition.

6. Self-Care Strategies: While waiting for your next appointment, focus on self-care strategies that can help alleviate some symptoms. Ensure you are getting adequate rest, staying hydrated, and engaging in light physical activity if possible. Mindfulness practices, such as meditation or deep-breathing exercises, can also help manage anxiety and improve your overall sense of well-being.

7. Monitoring Symptoms: Keep a journal of your symptoms, noting when they occur and their severity. This information can be invaluable for your healthcare provider in determining the best course of action during your next visit.

In conclusion, while it is normal to experience some side effects when adjusting to new medications, it is essential to monitor these symptoms closely and maintain open communication with your healthcare provider. They can help you navigate these changes and ensure that your treatment for depression remains effective and manageable. Remember, you are not alone in this journey, and seeking help is a sign of strength.

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