Creatinine Levels and Kidney Function: What You Need to Know - Internal Medicine

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I had a health check-up last year, and my blood urea nitrogen (BUN) was 16, and creatinine was 0.9.
Recently, due to bone spurs, I took anti-inflammatory medication, and during a follow-up health check-up, my BUN was 16.1 and creatinine was 0.8.
Can you please advise if my kidney function has decreased?

Wang, 50~59 year old female. Ask Date: 2005/06/22

Dr. Yang Jun reply Internal Medicine


Hello: In response to your question, Blood Urea Nitrogen (BUN) and Creatinine (Cr) are indicators of kidney function.
The normal values are: BUN is 8-20 mg/dL, and Cr is 0.4-1.4 mg/dL.
Therefore, your kidney function is normal.

Reply Date: 2005/06/22

More Info


Understanding creatinine levels and kidney function is crucial for assessing overall health, especially when there are changes in medication or health status. In your case, you mentioned that your blood urea nitrogen (BUN) levels are stable at around 16, while your creatinine levels have slightly fluctuated between 0.8 and 0.9. These values are generally within the normal range for most adults, where normal creatinine levels typically range from 0.6 to 1.2 mg/dL, depending on factors such as muscle mass, age, and sex.

Creatinine is a waste product generated from muscle metabolism and is usually filtered out of the blood by the kidneys. Therefore, measuring creatinine levels is a common way to evaluate kidney function. When kidney function declines, creatinine levels tend to rise because the kidneys are less effective at filtering this waste product from the blood. Conversely, stable or low creatinine levels, especially in the context of normal BUN levels, often indicate that kidney function is intact.

The BUN-to-creatinine ratio is another important metric. In healthy individuals, this ratio typically falls between 10:1 and 15:1. A normal BUN level alongside a normal creatinine level suggests that the kidneys are functioning well. In your case, since both BUN and creatinine levels are stable and within normal ranges, it is unlikely that there is significant kidney impairment.

However, you mentioned that you have been taking medication for bone spurs. Some medications can affect kidney function, either positively or negatively. Nonsteroidal anti-inflammatory drugs (NSAIDs), for example, can sometimes lead to kidney issues if used long-term or in high doses. It’s essential to monitor kidney function regularly if you are on such medications, especially if you have other risk factors for kidney disease, such as diabetes or hypertension.

If you are concerned about your kidney function or the effects of your medication, it would be wise to discuss this with your healthcare provider. They may recommend additional tests, such as a urinalysis or imaging studies, to assess kidney health more thoroughly. Furthermore, if you notice any symptoms such as swelling, changes in urination patterns, or fatigue, you should seek medical advice promptly.

In summary, based on the information provided, your kidney function appears to be stable, with both BUN and creatinine levels within normal limits. However, continuous monitoring and open communication with your healthcare provider are essential, especially when taking medications that could impact kidney health. Regular check-ups can help ensure that any potential issues are identified early, allowing for timely intervention if necessary.

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