Managing High Triglycerides and Liver Health: A Guide for Patients - Gastroenterology and Hepatology

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Triglycerides


Hello doctor, my question is that after a health check, I found my triglycerides to be 800, SGPT (ALT) 40, SGOT 41, and SGPT 61.
What should I do? I have also been diagnosed with polycystic ovary syndrome and fatty liver.
Will taking Diane (Diane-35) or blood sugar-lowering medication (Kuroza) affect my liver? What should I do?

Fenfen, 20~29 year old female. Ask Date: 2005/08/20

Dr. Yuan Hongdao reply Gastroenterology and Hepatology


Hello, if your liver enzymes are elevated due to fatty liver (assuming there is no hepatitis B or C, alcohol consumption, other medications, or biliary diseases), then treatment should focus on fatty liver.
Common causes of fatty liver include obesity, diabetes, alcohol consumption, and hyperlipidemia.
First, weight loss may be necessary, blood sugar levels should be well-controlled, regular exercise is important, and it is advisable to reduce the intake of greasy foods and alcohol.
With triglycerides at 800, if lifestyle changes such as exercise and dietary control are ineffective, consider medication to lower triglycerides.
Dailian contains female hormones, which may cause an increase in triglycerides; please discuss with your physician whether you should continue taking it.
Sincerely, Dr.
Yuan Hongdao, Internal Medicine.

Reply Date: 2005/08/20

More Info


Managing high triglycerides and liver health is crucial, especially for patients with underlying conditions such as polycystic ovary syndrome (PCOS) and fatty liver disease. Your recent health check indicates elevated triglycerides at 800 mg/dL, along with slightly elevated liver enzymes (SGPT/ALT at 40 and SGOT/AST at 41). These findings suggest that your liver may be under stress, likely due to the high triglyceride levels and possibly exacerbated by your fatty liver condition.


Understanding the Implications
High triglycerides can lead to a range of health issues, including pancreatitis and cardiovascular diseases. In the context of liver health, elevated triglycerides are often associated with non-alcoholic fatty liver disease (NAFLD), which can progress to more severe liver conditions, including non-alcoholic steatohepatitis (NASH) and cirrhosis if not managed properly. The liver enzymes (ALT and AST) you mentioned are indicators of liver inflammation or damage. While your levels are not alarmingly high, they do warrant attention, especially given your triglyceride levels.


Management Strategies
1. Dietary Modifications:
- Reduce Sugar and Refined Carbohydrates: High sugar intake can significantly raise triglyceride levels. Focus on whole grains, fruits, and vegetables.

- Healthy Fats: Incorporate sources of omega-3 fatty acids, such as fatty fish (salmon, mackerel), walnuts, and flaxseeds, which can help lower triglyceride levels.

- Limit Saturated and Trans Fats: These fats can worsen liver health and increase triglycerides. Avoid fried foods, processed snacks, and fatty cuts of meat.

2. Weight Management:
- If you are overweight, losing even a small percentage of your body weight can help lower triglycerides and improve liver health. Aim for a gradual weight loss through a combination of diet and exercise.

3. Physical Activity:
- Regular exercise can help lower triglycerides and improve liver function. Aim for at least 150 minutes of moderate-intensity aerobic activity each week, along with strength training exercises.

4. Medication Review:
- You mentioned taking medications such as Diane-35 (often used for PCOS) and Kuroz (which may be a glucose-lowering agent). It's essential to discuss with your healthcare provider how these medications may affect your liver health and triglyceride levels. Some medications can have side effects that impact liver function, so regular monitoring is crucial.

5. Regular Monitoring:
- Given your elevated triglycerides and liver enzymes, regular follow-up appointments with your healthcare provider are essential. This may include periodic blood tests to monitor liver function and triglyceride levels, as well as imaging studies to assess the degree of fatty liver.

6. Consider Supplements:
- Some supplements, such as omega-3 fatty acids, may help lower triglyceride levels. However, consult your healthcare provider before starting any new supplements, especially considering your liver health.


Conclusion
Managing high triglycerides and liver health requires a comprehensive approach that includes lifestyle modifications, dietary changes, and regular medical follow-up. Given your specific health conditions, it is crucial to work closely with your healthcare provider to tailor a management plan that addresses both your triglyceride levels and liver health. By making informed choices and staying proactive about your health, you can significantly improve your overall well-being and reduce the risk of complications associated with high triglycerides and fatty liver disease.

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