Is It Safe to Use Diane for Birth Control with New Heart Medications? - Obstetrics and Gynecology

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Is it safe to use Diane continuously for contraception?


Hello, doctor.
I would like to ask you about my current situation.
I have just started taking medication for suspected hypertension, specifically Nakamide 2.5 mg, along with the following medications: Bokeyd (100), Herbesser (30), and Inderal (10).
I was recently diagnosed with possible symptoms of angina, and my doctor prescribed these medications for treatment.
I would like to know if I can still use Dailian for contraception or if I should discontinue it.

Ci, 30~39 year old female. Ask Date: 2006/06/01

Dr. Li Guanghan reply Obstetrics and Gynecology


Hello: Oral contraceptives can increase the risk of blood clots; therefore, patients with cardiovascular diseases should use alternative methods for contraception.
Hsinchu Hospital, Department of Obstetrics and Gynecology.

Reply Date: 2006/06/01

More Info


When considering the use of Diane (Diane-35) for birth control in conjunction with new heart medications, it is essential to evaluate both the safety and potential interactions between these medications. Diane-35 is a combined oral contraceptive that contains cyproterone acetate and ethinyl estradiol, primarily used for contraception and to treat conditions like acne and hirsutism due to its anti-androgenic properties.
Given your recent diagnosis of possible angina and the initiation of medications such as Nakamide (a diuretic), Bokeyd (a beta-blocker), Herbesser (an antihypertensive), and Inderal (another beta-blocker), it is crucial to assess the implications of using Diane-35 alongside these treatments.

1. Safety of Combined Oral Contraceptives (COCs) with Heart Medications:
- COCs like Diane-35 can increase the risk of thromboembolic events, especially in women with pre-existing cardiovascular conditions or those taking medications that may also affect blood pressure or clotting. Since you have been diagnosed with symptoms suggestive of angina, this raises concerns about the cardiovascular risks associated with hormonal contraceptives.

- Medications such as Inderal (propranolol) and Bokeyd can lower heart rate and blood pressure, which may interact with the cardiovascular effects of Diane-35. While beta-blockers are often prescribed to manage hypertension and angina, the combination with estrogen-containing contraceptives may require careful monitoring.

2. Potential Risks:
- The use of Diane-35 in women with cardiovascular risk factors, including hypertension and potential coronary artery disease, may not be advisable. The estrogen component can lead to increased blood clotting, which poses a risk for women with existing heart conditions.

- It is also important to consider the side effects of Diane-35, which can include headaches, nausea, and mood changes, which may be exacerbated by the stress of managing a new heart condition.

3. Recommendations:
- It is highly recommended that you consult with both your cardiologist and your gynecologist before continuing or discontinuing Diane-35. They can provide a comprehensive evaluation of your cardiovascular health and the appropriateness of using hormonal contraception in your specific situation.

- If the decision is made to discontinue Diane-35, alternative contraceptive methods should be discussed. Non-hormonal options such as copper IUDs or barrier methods may be safer alternatives that do not carry the same risks associated with hormonal contraceptives.

4. Monitoring and Follow-Up:
- If you continue with Diane-35, close monitoring of your cardiovascular status is essential. Regular follow-ups with your healthcare providers will help ensure that any potential complications are identified early and managed appropriately.

In conclusion, while Diane-35 is effective for contraception, its use in the context of new heart medications and potential cardiovascular issues requires careful consideration. Prioritize discussions with your healthcare providers to make informed decisions that prioritize your overall health and well-being.

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