Natto vs. Lecithin: Which is Better for Preventing Vascular Thrombosis? - Cardiology

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Hello Doctor,
I am inquiring on behalf of my father, who is 71 years old.
Could you please advise which is more effective for preventing vascular embolism: "natto (enzyme)" or "lecithin"? How should one choose between the two? Thank you.
My father is currently taking lecithin, which is said to act as a "blood cleanser" to prevent vascular embolism.
Recently, I learned that natto also has a role in preventing vascular embolism, so he is considering taking natto enzyme.
However, we are unsure whether he should switch to natto or if he can use both together.
Thank you.
Best regards,
Jimmy

Jimmy, 30~39 year old female. Ask Date: 2008/11/12

Dr. Bu Shiyun reply Cardiology


Both of these belong to dietary supplements and have different functions.
Taking them together does not cause any conflict, as long as you adhere to the recommended dosage and do not exceed it.

Reply Date: 2008/11/12

More Info


Hello Jimmy,
Thank you for your inquiry regarding the use of Natto (fermented soybeans) and lecithin for preventing vascular thrombosis in your father, who is 71 years old. Both Natto and lecithin have been discussed in the context of cardiovascular health, but they work through different mechanisms and have varying levels of scientific support.

Natto and Its Benefits:
Natto contains an enzyme called nattokinase, which is believed to have fibrinolytic properties, meaning it can help dissolve blood clots. Some studies suggest that nattokinase may improve blood circulation and reduce the risk of thrombosis by breaking down fibrin, a protein involved in blood clotting. However, while there is some evidence supporting these claims, it is important to note that the clinical evidence is not as robust as that for conventional anticoagulants like warfarin. Therefore, while nattokinase may offer some benefits, it should not be considered a substitute for prescribed anticoagulant therapy without consulting a healthcare professional.

Lecithin and Its Role:
Lecithin, on the other hand, is a phospholipid that is often touted for its ability to support lipid metabolism and promote healthy cholesterol levels. It is thought to help emulsify fats in the body, which can aid in the prevention of atherosclerosis (hardening of the arteries). While lecithin may contribute to overall cardiovascular health, its direct effects on preventing vascular thrombosis are less clear compared to those of nattokinase.

Combining Natto and Lecithin:
Regarding whether to switch from lecithin to nattokinase or to use both, it is essential to consider your father's overall health status, any existing medical conditions, and medications he may be taking. If he is currently on anticoagulant therapy, such as warfarin, introducing nattokinase could potentially increase the risk of bleeding, as both nattokinase and warfarin affect blood clotting. Therefore, it is crucial to consult with his healthcare provider before making any changes to his supplement regimen.

Recommendations:
1. Consult a Healthcare Provider: Before making any changes, it is vital to discuss with your father's doctor or a qualified healthcare professional. They can provide personalized advice based on his medical history and current medications.


2. Monitor for Interactions: If your father is taking anticoagulants, be cautious about adding nattokinase, as it may enhance the effects of these medications, leading to an increased risk of bleeding.

3. Consider Dietary Sources: Instead of relying solely on supplements, incorporating foods rich in omega-3 fatty acids (like fish), fruits, vegetables, and whole grains can support cardiovascular health and may help reduce the risk of thrombosis.

4. Regular Monitoring: If your father is on anticoagulant therapy, regular monitoring of his blood coagulation levels (such as INR for warfarin) is essential to ensure that he remains within the therapeutic range.

In conclusion, while both nattokinase and lecithin have potential benefits for cardiovascular health, they should be used with caution, especially in individuals on anticoagulant therapy. A collaborative approach with healthcare providers will ensure that your father's treatment plan is safe and effective. Thank you for reaching out, and I hope this information helps you make an informed decision for your father's health.

Best regards.

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