Abnormal Health Check Results: What to Do Next? - Family Medicine

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Health check-up issues?


C-reactive protein (CRP) abnormal positive, thyroid hormone T3 elevated at 1.5, red blood cell count (RBC) abnormal at 6.41, mean corpuscular volume (MCV) abnormal at 66.1, mean corpuscular hemoglobin (MCH) abnormal at 20.7, hemoglobin (Hgb) abnormal at 13.3.
Due to working night shifts, my health is not optimal, and I am unsure if further testing is necessary.

Xiao An An, 30~39 year old female. Ask Date: 2009/02/23

Dr. Cai Mengru reply Family Medicine


Dear Mr.
Xiao An An,
Hello, your report mainly has three issues: the abnormal levels of red blood cells (RBC), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and hemoglobin (Hgb) indicate the same condition, suggesting that you may be a carrier of beta-thalassemia.
To confirm this, further testing is required.

As for the elevated C-reactive protein (CRP), it indicates inflammation, but there could be many underlying causes.
If you are experiencing any discomfort, you should discuss this with your physician to see if it can explain this abnormality.

T3 is a measure of thyroid function and cannot be interpreted in isolation.
If you also had tests for TSH and free T4, an isolated elevation may not necessarily indicate hyperthyroidism.
If you only had this one test done, you may need to consult your physician for a comprehensive evaluation.
Wishing you peace and health.
Sincerely,
Dr.
Tsai Meng-Ju
Attending Physician, Family Medicine Department
Taoyuan General Hospital, Ministry of Health and Welfare

Reply Date: 2009/02/23

More Info


When interpreting abnormal health check results, it is crucial to understand the implications of each abnormal value and the potential underlying conditions they may indicate. Based on the results you've provided, several key indicators stand out, including elevated C-reactive protein (CRP), high thyroid hormone levels (T3), and abnormalities in red blood cell (RBC) parameters such as mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and hemoglobin (Hgb).


C-Reactive Protein (CRP)
CRP is a marker of inflammation in the body. An elevated CRP level suggests that there is some form of inflammation or infection present. This could be due to a variety of reasons, including acute infections, chronic inflammatory diseases, or even stress. Given that you mentioned working night shifts, it is possible that your body is under stress, which can also elevate CRP levels. It would be advisable to follow up with your healthcare provider to determine the cause of the inflammation. They may recommend further tests or evaluations to identify any underlying conditions.


Thyroid Hormones (T3)
A high level of T3 can indicate hyperthyroidism, a condition where the thyroid gland is overactive. Symptoms of hyperthyroidism can include weight loss, increased heart rate, anxiety, and heat intolerance. If you are experiencing any of these symptoms, it is essential to discuss them with your doctor. They may suggest additional tests, such as TSH (Thyroid Stimulating Hormone) and T4 levels, to get a complete picture of your thyroid function.


Red Blood Cell Parameters
Your RBC count is elevated at 6.41, which may indicate polycythemia, a condition characterized by an increased number of red blood cells. This can occur due to various factors, including chronic hypoxia (low oxygen levels), dehydration, or other underlying health issues. The MCV of 66.1 is notably low, indicating microcytic anemia, which is often associated with iron deficiency or thalassemia. The MCH of 20.7 is also low, suggesting that the hemoglobin content in each red blood cell is reduced.


Hemoglobin (Hgb)
Your hemoglobin level of 13.3 is within the normal range for many adults, but in conjunction with the low MCV and MCH, it suggests that while you may not be anemic in the traditional sense, the quality of your red blood cells may be compromised. This could lead to symptoms such as fatigue, weakness, and decreased exercise tolerance.


Next Steps
Given these findings, it is crucial to take the following steps:
1. Consult Your Healthcare Provider: Discuss these results with your doctor, who can provide a comprehensive evaluation based on your medical history, symptoms, and lifestyle factors.

2. Further Testing: Your doctor may recommend additional blood tests, including iron studies (serum iron, ferritin, total iron-binding capacity), vitamin B12 and folate levels, and possibly a reticulocyte count to assess bone marrow function.

3. Lifestyle Modifications: If your lifestyle, such as working night shifts, is contributing to your health issues, consider discussing strategies to improve your overall well-being. This may include dietary changes, stress management techniques, and ensuring adequate sleep.

4. Monitor Symptoms: Keep track of any symptoms you may experience, such as fatigue, changes in weight, or mood fluctuations, and report these to your healthcare provider.

5. Follow-Up Appointments: Regular follow-ups with your healthcare provider will be essential to monitor your condition and adjust any treatment plans as necessary.

In conclusion, while your health check results indicate some abnormalities, they also provide an opportunity for further investigation and management. By working closely with your healthcare provider, you can develop a plan that addresses these issues and supports your overall health.

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