Is It Normal for My Baby's Vaccination Site to Swell and Pus? - Pediatrics

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Newborn vaccinations


Hello, Doctor.
My baby is over 3 months old and has received vaccinations for more than a month now (5-in-1, rotavirus, pneumonia, etc.).
There is still a sizable red, swollen lump at the injection site on his arm, and it appears to be pus-filled.
Is this situation normal, or should I take him to see a doctor? Thank you.

Jia Yi, 20~29 year old female. Ask Date: 2009/03/20

Dr. He Shenglong reply Pediatrics


Hello: If the BCG vaccine is administered, there may be purulent discharge and scabbing at the injection site.
If your baby has received other vaccinations, redness, swelling, and purulence lasting for more than a month may indicate inflammation.
It is recommended that you take your baby to see a doctor for evaluation.
Thank you for your message!

Reply Date: 2009/03/20

More Info


It is not uncommon for babies to experience some reactions at the vaccination site, including swelling and redness. However, the presence of pus and a significant lump at the injection site, especially one that persists for over a month, warrants further evaluation.

When a vaccine is administered, the body’s immune response can cause localized reactions. These reactions may include:
1. Redness and Swelling: This is a typical inflammatory response as the immune system reacts to the vaccine. It usually resolves within a few days.

2. Pain or Tenderness: The injection site may be sore, which is also a normal reaction.

3. Lumps or Nodules: Sometimes, a small lump can form at the injection site due to the accumulation of immune cells. This is generally harmless and should resolve over time.

However, if the lump is accompanied by pus, it may indicate an infection at the injection site, which is not typical. Signs of infection can include:
- Increased redness and swelling
- Warmth at the site
- Pus or drainage
- Fever or irritability in the baby
Given that your baby has had a lump with pus for over a month, it is advisable to consult a healthcare professional. They can assess the site and determine if any treatment is necessary, such as antibiotics if an infection is present.

In terms of vaccination safety, vaccines are administered using sterile, single-use syringes and needles to minimize the risk of infection. Healthcare providers are trained to follow strict protocols to ensure that each vaccine is given safely. However, if there is any doubt about the cleanliness of the procedure or if there are concerns about the equipment used, it is always best to discuss these concerns with your healthcare provider.

In addition, while it is essential for babies to receive their vaccinations on schedule, it is equally important for parents to monitor their children for any unusual reactions following vaccination. If you notice anything concerning, such as prolonged swelling, pus, or any signs of systemic illness (like fever or lethargy), do not hesitate to seek medical advice.

In summary, while some localized reactions to vaccinations are normal, the presence of pus and a persistent lump is not typical and should be evaluated by a healthcare professional. Early intervention can help address any potential issues and ensure your baby’s health and well-being.

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