Side effects of Zhi Shan tablets?
Hello, pharmacist.
Could you please tell me what side effects are associated with the medication "Zhi Shan Pian"? Is it considered a high-alert medication? The doctor mentioned it could potentially cause liver function abnormalities, but my blood test results from two weeks ago seemed normal.
I need to take three tablets a week along with one folic acid tablet, and I am now in the sixth week of treatment.
What is its efficacy? Why is it used to replace corticosteroids? The doctor said I could gradually reduce my corticosteroid dosage this month, but I feel like my allergy frequency has actually increased (for example, my allergic rhinitis had calmed down for a while, but suddenly worsened two days ago).
Additionally, could you tell me the side effects of "Qu Yi Lei Mo Yi Pian"? I always feel very fatigued and my legs feel weak after taking it.
Is this medication a long-acting treatment for allergies? Because if I have a sudden allergic reaction, it seems ineffective, while "Min Fu" works within 1-3 hours.
Is it really okay to take so many medications?
Xiao Jie, 10~19 year old female. Ask Date: 2009/08/25
Dr. Zeng Biru reply Pharmacology
Trexan Tab (Active ingredient: Methotrexate 2.5mg)
1.
Indication: Methotrexate is a folate antagonist primarily used to inhibit DNA synthesis and also directly affects RNA and protein synthesis.
2.
Side effects: Common - ulcerative stomatitis, glossitis, gingivitis, headache, leukopenia, thrombocytopenia.
Severe - hepatotoxicity, liver cirrhosis, bone marrow suppression, pneumonia.
3.
Co-administration with folic acid can reduce the occurrence of oral ulcers and gastrointestinal side effects.
4.
This medication is classified as a high-alert drug.
Levocetirizine Dihydrochloride Film-Coated Tablets (Active ingredient: Levocetirizine dihydrochloride 5mg)
1.
Side effects: Commonly reported include dry mouth, headache, fatigue, drowsiness, weakness, rhinitis, pharyngitis, abdominal pain, and headache.
2.
This medication is a second-generation (H1 selective) antihistamine, which has fewer side effects such as drowsiness and palpitations.
3.
Minlife Tab (Active ingredient: Loratadine 10mg) is also a second-generation (H1 selective) antihistamine, with comparable drug action, dosing intervals, sedative effects, and antihistamine activity.
4.
Please follow the physician's instructions for medication use and ensure timely follow-up appointments.
Reply Date: 2009/08/25
More Info
Understanding the side effects of medications, especially those used for managing allergies, is crucial for ensuring patient safety and effective treatment. In your case, you are asking about Zhi Shan Pills (治善錠), which is often used in the context of allergy management, and its potential side effects, particularly concerning liver function, as well as its role in replacing corticosteroids.
Zhi Shan Pills (治善錠) Overview
Zhi Shan Pills are typically used in Traditional Chinese Medicine (TCM) for their purported ability to modulate the immune response and alleviate symptoms associated with allergies. The exact composition can vary, but they often contain herbal ingredients that are believed to have anti-inflammatory and immune-regulating properties.
#
Side Effects and Concerns
1. Liver Function: As you mentioned, there is a concern regarding liver function abnormalities associated with Zhi Shan Pills. While many herbal medications are generally considered safe, they can sometimes lead to hepatotoxicity, especially if taken in high doses or for prolonged periods. Regular monitoring of liver function tests (LFTs) is advisable, particularly if you have a history of liver issues or are taking other medications that may affect liver function.
2. High Alert Medication: If your healthcare provider has classified Zhi Shan Pills as a "high alert" medication, it indicates that there is a significant risk of causing harm if used incorrectly. This classification often applies to medications that require careful monitoring and dosage adjustments.
3. Allergy Frequency: You noted an increase in allergy symptoms despite taking Zhi Shan Pills. This could be due to several factors, including the natural variability of allergic reactions, potential interactions with other medications, or the possibility that the Zhi Shan Pills are not adequately addressing your specific allergic triggers. It’s essential to communicate these changes to your healthcare provider, as they may need to reassess your treatment plan.
Alternatives and Corticosteroid Reduction
The rationale behind using Zhi Shan Pills as an alternative to corticosteroids is primarily to reduce the side effects associated with long-term steroid use, such as weight gain, osteoporosis, and increased risk of infections. Corticosteroids are effective for managing inflammation but are not without their drawbacks, particularly when used chronically.
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Efficacy and Timing
1. Efficacy: The effectiveness of Zhi Shan Pills can vary from person to person. Some individuals may experience significant relief from allergy symptoms, while others may find them less effective compared to traditional antihistamines or corticosteroids.
2. Timing of Relief: You mentioned that "敏福" (likely referring to a specific antihistamine) provides quicker relief within 1-3 hours. This is typical for many antihistamines, which are designed for rapid action. In contrast, herbal remedies like Zhi Shan Pills may take longer to exert their effects, as they often work by gradually modulating the immune response rather than providing immediate symptom relief.
Regarding "驅異肋膜衣錠"
This medication, which may be an antihistamine or another type of allergy treatment, can also have side effects. Common side effects of antihistamines include drowsiness, fatigue, and muscle weakness, which you have experienced. If you find that this medication makes you feel excessively tired or weak, it may be worth discussing with your healthcare provider. They might consider adjusting your dosage or switching you to a different medication that may not have the same sedative effects.
Conclusion
In summary, while Zhi Shan Pills may offer an alternative to corticosteroids for managing allergies, it is essential to monitor for potential side effects, particularly concerning liver function. If you are experiencing increased allergy symptoms or side effects from your current regimen, it is crucial to consult with your healthcare provider. They can help tailor your treatment plan to better suit your needs, ensuring that you achieve optimal control of your allergy symptoms while minimizing risks. Always keep an open line of communication with your healthcare team regarding any changes in your condition or concerns about your medications.
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