There are contraindications regarding the combination of beta-carotene and lutein?
Hello Dr.
Hu, I would like to ask you the following questions:
1.
I have been taking a lutein supplement containing beta-carotene (50 mg of beta-carotene daily) for one to two years.
Recently, I read an article by a pharmacist online stating that "there is a contraindication between beta-carotene and lutein; excessive intake of beta-carotene can affect the retina, and it may also interfere with the absorption of lutein." Do you agree with this? Should I consider switching to another lutein supplement?
2.
The pharmacist recommended taking "high-dose pure lutein 30 mg" to promote healthier and more stable retinas in both eyes.
Do you think it is advisable for me to take this "high-dose pure lutein 30 mg"? (I had retinal detachment in my left eye in 2006 due to high myopia and underwent two retinal reattachment surgeries, and I have also received outpatient retinal laser treatment in both eyes to stabilize and improve retinal health.)
Xiao Lai, 30~39 year old female. Ask Date: 2009/12/27
Dr. Hu Yusheng reply Ophthalmology
Hello: High doses of beta-carotene are not suitable for smokers, as they may increase the risk of lung cancer.
I have no research on your other questions (these are food products, not medications).
Wishing you peace and health.
Reply Date: 2009/12/27
More Info
When it comes to eye health, the interplay between various nutrients, particularly beta-carotene and lutein, is a topic of considerable interest. Both of these compounds are carotenoids, which are pigments found in plants that have antioxidant properties and are believed to play a role in eye health. However, there are some nuances to their interaction and effects that are worth discussing.
1. Beta-Carotene and Lutein Interaction: The concern you mentioned regarding beta-carotene potentially affecting lutein absorption is not widely supported by robust clinical evidence. While both compounds are fat-soluble and can be absorbed better when consumed with dietary fats, there is no strong consensus that beta-carotene directly inhibits lutein absorption. However, excessive intake of beta-carotene, particularly in supplement form, has been associated with certain health risks, especially in smokers, where it may increase the risk of lung cancer. For the general population, moderate consumption of beta-carotene through diet (like carrots, sweet potatoes, and leafy greens) is considered safe and beneficial.
2. Lutein Dosage Recommendations: As for the recommendation of taking a higher dose of lutein, such as 30 mg daily, this is generally considered safe for most individuals. Studies have shown that lutein can help filter harmful blue light and protect the retina, potentially reducing the risk of age-related macular degeneration (AMD). The typical dietary intake of lutein is around 6-10 mg per day, so a supplement providing 30 mg may be beneficial, especially for individuals with a history of retinal issues, like yourself. However, it is crucial to consult with your healthcare provider before making any changes to your supplement regimen, especially considering your medical history of retinal detachment and surgeries.
3. Eye Health Considerations: Given your history of high myopia and retinal surgeries, maintaining optimal eye health is paramount. In addition to lutein and beta-carotene, other nutrients such as zeaxanthin, omega-3 fatty acids, vitamin C, vitamin E, and zinc are also important for eye health. A balanced diet rich in leafy greens, colorful fruits, and fatty fish can provide these nutrients naturally.
4. Monitoring Eye Health: Regular eye examinations are essential, especially for someone with your medical background. It would be wise to discuss your supplement intake with your ophthalmologist, who can provide personalized advice based on your eye health status and any potential interactions with other medications or treatments you may be undergoing.
In summary, while there is no strong evidence to suggest that beta-carotene negatively impacts lutein absorption, it is essential to be mindful of the dosage and potential risks associated with high intake of any supplement. A balanced approach that includes a variety of nutrients through diet, along with appropriate supplementation as needed, is the best strategy for maintaining eye health. Always consult with your healthcare provider before making significant changes to your supplement routine, especially considering your unique medical history.
Similar Q&A
Does Higher Lutein Content in Supplements Improve Eye Health?
Hello, nutritionist: I would like to ask about lutein and vision health. Does a higher content of lutein in commercially available supplements lead to better outcomes for vision? Besides lutein, should I also include additional supplements, such as anthocyanins, vitamin A, or DHA...
Dr. Xie Peiru reply Nutrition
Hello: Lutein is a carotenoid that naturally occurs in various fruits and vegetables, such as kale, spinach, mustard greens, dark green broccoli, corn, as well as in kiwifruit, grapes, orange juice, zucchini, and pumpkin, all of which contain varying amounts of lutein. Lutein act...[Read More] Does Higher Lutein Content in Supplements Improve Eye Health?
The Dual Role of Carotenoids: Antioxidants or Prooxidants?
Hello, the carotenoids are strong antioxidants, but under certain conditions where other oxidants are present, they can also act as prooxidants. β-Carotene, due to this property, has been associated with an increased risk of lung cancer in smokers when taken in high doses. The β-...
Dr. Cai Xiuwen reply Nutrition
Hello! Some studies have found a correlation between high doses of beta-carotene and cancer incidence, with current research primarily focusing on high-dose nutritional supplements. The mechanisms behind these findings remain unclear; therefore, it is advisable to adhere to the r...[Read More] The Dual Role of Carotenoids: Antioxidants or Prooxidants?
Understanding the Impact of Carotenoids and Lutein on Health
1. There are many articles online suggesting that consuming beta-carotene and lutein together may reduce the absorption of lutein. However, there are still products on the market that contain both ingredients. The rationale behind this may be that the benefits of both nutrients c...
Dr. Hou Fangmin reply Pharmacology
Hello: 1. Beta-carotene is a precursor of vitamin A (Provitamin A), while lutein is an important systemic antioxidant. It is the most effective carotenoid in inhibiting lipid peroxidation and plays a key role in the antioxidant mechanism alongside other antioxidants in mitigati...[Read More] Understanding the Impact of Carotenoids and Lutein on Health
Impact of Infrared and UV Light on Eye Health and Essential Nutrients
Hello, Doctor! I have three questions to ask you: 1. Both infrared and ultraviolet light can affect eye health. I would like to know if the flames from cooking stoves, barbecue grills, and candles can also harm the eyes, and how can we reduce this damage? 2. Besides vitamins A...
Dr. Gao Pilin reply Ophthalmology
Hello Ms. Li: Everyday activities rarely cause eye injuries, so please rest assured. Infrared light typically does not cause harm; wearing UV-protective sunglasses outdoors can help reduce risks. Lutein and zeaxanthin are essential nutrients for the retina, and supplementing them...[Read More] Impact of Infrared and UV Light on Eye Health and Essential Nutrients
Related FAQ
(Ophthalmology)
Lutein(Nutrition)
Contact Lenses(Ophthalmology)
Retinal Degeneration(Ophthalmology)
Blue Light(Ophthalmology)
Nearsightedness(Ophthalmology)
Color Blindness(Ophthalmology)
Exposure To Bright Light(Ophthalmology)
Conjunctiva(Ophthalmology)
Eye Allergies(Ophthalmology)