Managing Epilepsy Medication: Concerns and Side Effects After Injury - Pharmacology

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Medication-related issues


Hello Dr.
Liao,
Thank you for taking the time to respond.
I was in a car accident and suffered a skull base fracture and a concussion.
It has now been three months.
The doctor prescribed me 4 to 5 different medications, but currently emphasizes that I must not stop taking Aleviatin 100mg, which I take three capsules every night, while the other medications are up to me.

I have a concern regarding the epilepsy medication.
A friend of mine also suffered a head injury, and he recently shared that he stopped taking his epilepsy medication after a month because his doctor said it could affect his liver.
He is now self-supplementing with B vitamins and B12.

I would like to ask the pharmacist if taking the epilepsy medication for three months is too long and if there could be any side effects.
Is it safe for me to self-supplement with B vitamins? Currently, I feel a bit of heaviness in my head, my balance is still somewhat off, and my limbs feel weak and sore.

I would appreciate your guidance on this matter.
Thank you very much, and I wish you success in your work.

Xiao Gui, 30~39 year old female. Ask Date: 2010/04/13

Dr. Liao Huiling reply Pharmacology


Hello! It is recommended that you use Aleviatin as directed by your physician.
Please also have your doctor evaluate whether you can discontinue the medication.
All medications have side effects, but the severity can vary from person to person.
If you need to take Aleviatin long-term, please prioritize your condition.
If you experience any adverse symptoms, please inform your attending physician.
Wishing you health and happiness!

Reply Date: 2010/04/13

More Info


Managing epilepsy medication after a traumatic brain injury can be a complex and challenging process. Your situation, involving a car accident that resulted in a skull base fracture and concussion, is not uncommon. It is essential to understand that the medications prescribed for epilepsy, such as Aleviatin (which contains lamotrigine), are crucial for controlling seizures and preventing further neurological damage.
Firstly, it is important to recognize that the duration and dosage of your medication are determined by your healthcare provider based on your specific medical history, the severity of your condition, and your response to treatment. The fact that your doctor has emphasized the importance of not stopping Aleviatin suggests that they believe it is necessary for your ongoing seizure management. Stopping or altering the dosage of epilepsy medication without medical supervision can lead to increased seizure frequency or severity, which can be dangerous.

Regarding your friend's experience with discontinuing their medication, it is vital to understand that each individual's situation is unique. While some patients may tolerate a reduction or cessation of medication, others may not. The concern about liver health is valid, as certain antiepileptic drugs can have hepatotoxic effects, but this is typically monitored through regular blood tests. If you have concerns about liver function or side effects, it is essential to discuss these with your healthcare provider, who can evaluate your liver function and adjust your treatment plan if necessary.

As for the side effects you are experiencing, such as a heavy feeling in your head, balance issues, and muscle weakness, these can be associated with both the medications and the underlying effects of your brain injury. Common side effects of antiepileptic drugs include dizziness, fatigue, and cognitive changes. It is crucial to communicate these symptoms to your doctor, as they may need to adjust your medication or explore other underlying causes.

Regarding the supplementation of B vitamins, particularly B12, it is generally considered safe to take B vitamins, as they are water-soluble and excess amounts are typically excreted through urine. However, it is always best to consult with your healthcare provider before starting any new supplements, especially when you are on multiple medications. Some supplements can interact with medications, potentially affecting their efficacy or increasing side effects.

In summary, managing epilepsy after a traumatic brain injury requires careful monitoring and communication with your healthcare provider. Do not make any changes to your medication regimen without consulting your doctor. Discuss your concerns about side effects and the possibility of supplementing with B vitamins during your next appointment. Your health and safety should always come first, and your doctor can provide the best guidance tailored to your specific needs.

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