Persistent Edema in Elderly Patients with Diabetes and Hypertension - Internal Medicine

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Persistent edema


Hello Dr.
Lee: My mother is 78 years old and has a history of hypertension and diabetes.
This year, she has experienced persistent edema in both legs for quite some time.
She also gets up to urinate about 2 to 3 times during the night, with a large volume of urine each time and it takes a long time.
What could be causing this phenomenon, and which specialist should I take her to see?

tina, 50~59 year old female. Ask Date: 2010/12/06

Dr. Li Zhiyao reply Internal Medicine


Tina: Hello, your mother has hypertension and diabetes, so it is important to consider whether there are any complications related to renal dysfunction.
Additionally, low albumin levels due to malnutrition or diabetic nephropathy causing proteinuria may also lead to edema.
I recommend that you take her to see a nephrologist.
Wishing you and your mother good health.

Reply Date: 2010/12/06

More Info


Persistent edema, particularly in elderly patients with underlying conditions such as diabetes and hypertension, can be a complex issue that requires careful evaluation. In your mother's case, her age, along with her medical history of hypertension and diabetes, adds layers of potential causes for her edema.
Edema, or swelling, can occur due to various reasons, including fluid retention, heart failure, kidney dysfunction, or even medication side effects. In elderly patients, the most common causes of persistent edema include:
1. Heart Failure: This is a condition where the heart is unable to pump blood effectively, leading to fluid accumulation in the legs and other parts of the body. Given that your mother has hypertension, she may be at an increased risk for heart-related issues.

2. Kidney Dysfunction: Diabetes can lead to diabetic nephropathy, a condition where the kidneys are damaged and unable to filter waste effectively. This can result in fluid retention and edema. The fact that your mother experiences increased urination at night (nocturia) could indicate that her kidneys are trying to compensate for fluid overload.

3. Medication Side Effects: Certain medications, especially those used to treat hypertension and diabetes, can cause edema as a side effect. For instance, some antihypertensive medications, particularly calcium channel blockers, can lead to peripheral edema. If your mother is taking any new medications or has had changes in her medication regimen, this could also be a contributing factor.

4. Venous Insufficiency: This condition occurs when the veins are unable to pump blood back to the heart effectively, leading to pooling of blood in the legs and resulting in swelling. This is more common in older adults and can be exacerbated by prolonged standing or sitting.

5. Dietary Factors: High sodium intake can lead to fluid retention, which may contribute to edema. It’s important to monitor her diet, especially her salt intake.

Given these potential causes, it is advisable to consult a healthcare professional who specializes in geriatric medicine or internal medicine. They can perform a thorough evaluation, including a physical examination, review of her medical history, and possibly order diagnostic tests such as blood tests, urine tests, or imaging studies to determine the underlying cause of her edema.

In the meantime, here are a few recommendations that may help manage her condition:
- Monitor Fluid Intake: Keep track of her fluid intake and output. This can help identify patterns and inform her healthcare provider.


- Elevate Legs: Encourage her to elevate her legs when sitting or lying down to help reduce swelling.

- Compression Stockings: These can help improve circulation in the legs and reduce swelling.

- Dietary Adjustments: Reducing salt intake can help minimize fluid retention.

- Regular Monitoring: Keep an eye on her blood pressure and blood sugar levels, as fluctuations can impact her overall health and contribute to edema.

In conclusion, persistent edema in elderly patients with diabetes and hypertension can arise from various factors, and it is essential to identify the underlying cause to provide appropriate treatment. Consulting with a healthcare professional will ensure that your mother receives the best care tailored to her specific needs.

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