Morganella Morganii: Implications for Urethritis and Treatment Options - Urology

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Hello.
If a semen analysis shows "Culture: Moderate mixed growth of Morganella morganii isolated," I would like to know if Morganella morganii is associated with non-gonococcal urethritis, chlamydia, or any sexually transmitted infection (or does the presence of this bacteria indicate a sexually transmitted infection)? What are the treatment options? If diagnosed with this condition, should one refrain from sexual activity with females? Additionally, if experiencing urethral itching, what type of tests should be conducted—blood tests or urine tests? Thank you.

k, 20~29 year old female. Ask Date: 2011/04/27

Dr. Xu Weikai reply Urology


K: Hello, this is a type of bacteria.
It is generally not classified as a sexually transmitted infection (STI).
However, it can potentially be transmitted to females through sexual intercourse, so it is recommended to temporarily use protective measures such as condoms.
After treating the bacteria with appropriate antibiotics, symptom management should be based on the symptoms that persist after treatment.
Additionally, incorporating cranberry can serve as an adjunctive therapy.
If there are any unclear points, feel free to ask again for further discussion and research.
This response is from Dr.
Hsu Wei-Kai, Director of the Urology Department, Taitung Hospital, Department of Health, Executive Yuan.

Reply Date: 2011/04/27

More Info


Morganella morganii is a gram-negative bacterium that is part of the normal flora of the human gastrointestinal tract. However, it can also be an opportunistic pathogen, particularly in cases of urinary tract infections (UTIs) and other infections. The presence of Morganella morganii in a semen culture indicates that it may be involved in the infection process, but it does not necessarily mean that you have a sexually transmitted infection (STI) such as gonorrhea or chlamydia.
Morganella morganii is not typically classified as a sexually transmitted pathogen. Instead, it is more commonly associated with infections that arise from the gastrointestinal tract or urinary tract. In the context of urethritis, its presence could suggest a non-specific urethritis, which may be due to various factors, including bacterial overgrowth or disruption of normal flora, rather than a classic STI.


Treatment Options
The treatment for infections caused by Morganella morganii typically involves the use of antibiotics. However, antibiotic susceptibility testing is essential, as this bacterium can exhibit resistance to various antibiotics. Commonly used antibiotics for treating infections caused by Morganella morganii include:
1. Ciprofloxacin: This fluoroquinolone antibiotic is often effective against Morganella morganii.

2. Trimethoprim-sulfamethoxazole (TMP-SMX): This combination antibiotic can also be effective, but susceptibility testing is recommended.

3. Piperacillin-tazobactam: This combination is sometimes used for more severe infections.

4. Ceftriaxone: This cephalosporin antibiotic may be effective, especially in cases of complicated infections.

It is crucial to follow your healthcare provider's recommendations regarding the choice of antibiotic and the duration of treatment.

Sexual Activity Considerations
If you have been diagnosed with an infection involving Morganella morganii, it is advisable to refrain from sexual activity until the infection has been adequately treated and resolved. This is important not only for your health but also to prevent potential transmission of bacteria to your partner.

Testing for Urethral Symptoms
If you are experiencing symptoms such as itching in the urethra, it is essential to seek medical evaluation. The appropriate tests may include:
1. Urinalysis: This test can help identify the presence of bacteria, white blood cells, and other indicators of infection in the urine.

2. Urine Culture: This test can identify the specific bacteria causing the infection and determine their antibiotic susceptibility.

3. Urethral Swab: In some cases, a healthcare provider may perform a swab of the urethra to test for STIs, including gonorrhea and chlamydia.

4. Blood Tests: While blood tests are not typically used to diagnose urethritis, they may be performed if there are concerns about systemic infection or other underlying conditions.

In summary, while the presence of Morganella morganii in a semen culture does not equate to a sexually transmitted disease, it can indicate a bacterial infection that requires treatment. It is essential to consult with your healthcare provider for appropriate testing, diagnosis, and treatment options. Additionally, avoiding sexual activity during treatment is advisable to ensure complete recovery and to protect your partner's health.

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