Edema: Causes and Concerns for Kidney Patients - Internal Medicine

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Edema of the legs?


Hello Dr.
Wu: I have chronic glomerulonephritis with proteinuria and hypertension, and I undergo blood tests every three months.
My kidney function is within normal limits, although my creatinine level occasionally exceeds 1.4 slightly.
The cardiologist suggested monitoring the situation.
Since last year, I have been experiencing suspected edema in my legs.
I asked the cardiologist about it, and he mentioned it might be due to obesity.
I have noticed that when I press on my legs, there is a dent that lasts about 3-5 seconds (sometimes it takes several minutes to return to normal).
Could you please advise if this qualifies as edema? Thank you for taking the time to respond, Dr.
Wu.

Dadi Shu, 40~49 year old female. Ask Date: 2014/03/04

Dr. Wu Jiyu reply Internal Medicine


1.
If pressing on the foot causes a dent that lasts about 3-5 seconds (sometimes several minutes) before recovering, does this count as edema? Answer: Yes, this is considered edema.

2.
Kidney function is within normal limits, but sometimes creatinine is slightly above 1.4.
Answer: If we calculate your age-adjusted glomerular filtration rate, it is only 55 mL/min/1.73 m², which indicates stage 3 chronic kidney disease.
3.
Chronic glomerulonephritis with proteinuria and hypertension.
Answer: It is recommended to consult a nephrologist for regular follow-up (blood tests for proteinuria) and to see a dietitian for a low-protein diet to help manage the condition.
Thank you for your inquiry; the nephrology department at Changhua Hospital cares about your health.

Reply Date: 2014/03/04

More Info


Hello, thank you for your question regarding edema and its implications for kidney patients. Edema, or swelling, occurs when excess fluid accumulates in the body's tissues. It can manifest in various parts of the body, most commonly in the legs, ankles, and feet. Given your medical history of chronic glomerulonephritis with proteinuria and hypertension, it is essential to understand the potential causes and concerns related to edema in your case.


Understanding Edema
Edema can arise from several factors, particularly in individuals with kidney issues. In your situation, the following causes may be relevant:
1. Kidney Function: The kidneys play a crucial role in regulating fluid balance in the body. When kidney function is compromised, as seen in chronic kidney disease (CKD), the kidneys may struggle to excrete excess fluid, leading to edema. Your creatinine levels, while slightly elevated at 1.4, indicate that your kidney function is still within a manageable range, but it is essential to monitor this closely.

2. Proteinuria: The presence of protein in the urine (proteinuria) can indicate kidney damage. Proteins help maintain oncotic pressure, which keeps fluid within the blood vessels. When protein levels drop due to kidney dysfunction, fluid can leak into surrounding tissues, causing edema.

3. Hypertension: High blood pressure can contribute to fluid retention. It can also lead to heart issues, which may exacerbate edema. If your heart is under strain, it may not pump effectively, leading to fluid accumulation in the lower extremities.

4. Obesity: As your cardiologist mentioned, obesity can contribute to edema. Excess body weight can put additional pressure on the veins in your legs, making it harder for blood to return to the heart, which can lead to swelling.

5. Medication Side Effects: Some medications, especially those used to treat hypertension or other conditions, can cause fluid retention as a side effect. It's important to review your medications with your healthcare provider to rule out this possibility.


Assessing Your Symptoms
The fact that you experience a "pitting" edema—where pressing on the swollen area leaves a temporary indentation—suggests that the swelling is indeed due to fluid retention. This is a common sign of edema and can be associated with various underlying conditions, including those related to kidney function.


Recommendations
1. Monitoring: Continue to monitor your kidney function through regular blood tests as advised by your nephrologist. Keeping track of your creatinine levels and other relevant markers will help assess any changes in your kidney health.

2. Dietary Adjustments: Consider a low-sodium diet, as sodium can contribute to fluid retention. Reducing salt intake may help alleviate some of the swelling. Additionally, maintaining a balanced diet rich in fruits, vegetables, and whole grains can support overall health.

3. Weight Management: If obesity is a contributing factor, working towards a healthier weight through diet and exercise may help reduce edema. Consult with a nutritionist or dietitian for personalized advice.

4. Physical Activity: Engaging in regular physical activity can improve circulation and help manage weight. Simple exercises, such as walking or leg lifts, can promote fluid movement and reduce swelling.

5. Elevate Your Legs: When resting, try to elevate your legs to help reduce swelling. This can assist in fluid drainage from the lower extremities.

6. Consult Your Healthcare Provider: If the edema persists or worsens, or if you experience additional symptoms such as shortness of breath, chest pain, or significant weight gain, seek immediate medical attention. Your healthcare provider may need to adjust your treatment plan or investigate further.

In conclusion, while edema can be concerning, understanding its potential causes and taking proactive steps can help manage your symptoms effectively. Regular communication with your healthcare team is vital to ensure your kidney health remains stable and to address any emerging issues promptly. Thank you for your inquiry, and I hope this information helps clarify your concerns regarding edema.

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