Weight Loss: Stress, Fatigue, and Health Concerns - Family Medicine

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Weight loss


I have been experiencing significant mental stress for over a month, worrying constantly.
In the last two weeks, I have started to feel fatigued and have the impression that I am not getting enough sleep.
Surprisingly, I have lost 7 kg in this month.
What could be the issue? I have undergone an upper endoscopy, which showed mild ulcers, and I also had a duodenal bleed.
However, both a colonoscopy and abdominal ultrasound were normal.

Wayne, 20~29 year old female. Ask Date: 2016/08/18

Dr. Zhang Hongwei reply Family Medicine


Hello, psychological stress is one of the causes of weight loss.
However, it is essential to rule out other underlying diseases, such as diabetes, hyperthyroidism, tuberculosis, or HIV.
I would like to know if you have experienced changes in appetite, increased thirst and urination, or fever.
Additionally, gastrointestinal ulcers could also be a contributing factor.
I recommend visiting a hospital for further examinations to exclude any diseases that may be causing the weight loss.
Thank you for your inquiry.

Reply Date: 2016/08/18

More Info


Experiencing significant weight loss, especially when accompanied by stress, fatigue, and sleep disturbances, can be concerning and may indicate underlying health issues. In your case, losing 7 kg over a month, particularly under high stress, warrants a closer examination of both psychological and physiological factors.

Firstly, stress can profoundly impact the body in various ways. When faced with stress, the body releases hormones such as cortisol and adrenaline. While these hormones can initially increase energy and focus, chronic stress can lead to fatigue, sleep disturbances, and changes in appetite. Some individuals may experience a decrease in appetite, leading to weight loss, while others may turn to food for comfort, resulting in weight gain. In your situation, it seems that the stress has led to a reduced appetite, contributing to your weight loss.

Moreover, the physical symptoms you are experiencing, such as fatigue and poor sleep quality, can further exacerbate the situation. Chronic fatigue can stem from various sources, including stress, inadequate nutrition, and underlying medical conditions. It is essential to evaluate your overall lifestyle, including your diet, exercise, and sleep patterns. A well-balanced diet is crucial for maintaining energy levels and overall health. If your diet lacks essential nutrients, it could contribute to feelings of fatigue and exacerbate stress.

Your previous medical evaluations, including endoscopies and ultrasounds, have ruled out significant gastrointestinal issues, which is a positive sign. However, the presence of a mild ulcer and duodenal bleeding indicates that your gastrointestinal health may still be affected by stress and dietary habits. Stress can lead to increased stomach acid production, which may aggravate ulcers and contribute to gastrointestinal discomfort. It is essential to manage stress effectively and consider dietary modifications that can support your gastrointestinal health.

In addition to physical health, mental health plays a crucial role in overall well-being. If you are experiencing persistent stress, anxiety, or depressive symptoms, it may be beneficial to consult with a mental health professional. Cognitive-behavioral therapy (CBT) and other therapeutic approaches can help you develop coping strategies for managing stress and anxiety. Additionally, mindfulness practices, such as meditation and yoga, can be effective in reducing stress and improving overall mental health.

It is also important to consider the possibility of other underlying medical conditions that could contribute to weight loss and fatigue. Conditions such as hyperthyroidism, diabetes, or chronic infections can lead to unintentional weight loss and fatigue. If you have not already done so, it may be worthwhile to discuss these possibilities with your healthcare provider and consider further testing if necessary.

In summary, the combination of stress, fatigue, and significant weight loss you are experiencing is concerning and should be addressed holistically. It is crucial to manage stress through lifestyle changes, including a balanced diet, regular physical activity, and adequate sleep. Seeking support from healthcare professionals, including mental health specialists, can provide you with the tools and strategies needed to navigate this challenging time. Remember, taking care of your mental and physical health is essential for achieving overall well-being.

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