Can I Take Heart Medication with Natto and Red Yeast Rice? - Cardiology

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Questions about medications for arrhythmia?


I would like to ask if it is safe to take Heart Regulating (心利正) medication prescribed by my doctor for my arrhythmia, along with my regular supplements of natto red yeast (which contains 15 mg of Monacolin K, 5000 FU of nattokinase, and 30 mg of Coenzyme Q10).
Can I take these two together if I space them out by one or two hours? Thank you.

Xiao Fang, 40~49 year old female. Ask Date: 2023/09/05

Dr. Wu Xueming reply Cardiology


Please allow at least one hour between doses to avoid affecting drug absorption.

Reply Date: 2023/09/05

More Info


When it comes to combining heart medications with supplements like natto and red yeast rice, it's essential to approach this matter with caution. Natto, which contains nattokinase, and red yeast rice, which contains monacolin K, are often used for their potential benefits in cardiovascular health, particularly in lowering cholesterol levels. However, they can also interact with prescription medications, especially those used for heart conditions.

In your case, you mentioned that you are taking a medication called "心利正" (likely a brand name for a heart medication, possibly a beta-blocker or antiarrhythmic agent) due to your arrhythmia. The primary concern with combining this medication with natto and red yeast rice lies in the potential for additive effects on blood pressure and heart rate, as well as the risk of increased side effects.


Key Considerations:
1. Monacolin K and Statins: Red yeast rice contains monacolin K, which is chemically identical to lovastatin, a statin used to lower cholesterol. If you are taking a statin or any medication that affects cholesterol levels, combining it with red yeast rice could lead to an increased risk of muscle pain or damage (myopathy) and liver issues. This is particularly important if you have pre-existing conditions affecting your liver or muscle health.

2. Nattokinase and Blood Thinning: Nattokinase is known for its fibrinolytic properties, meaning it can help dissolve blood clots. If you are on anticoagulants or antiplatelet medications, combining nattokinase could increase the risk of bleeding. This is crucial to consider, especially if your heart medication has any blood-thinning effects.

3. Timing and Absorption: You mentioned the possibility of taking these supplements a couple of hours apart from your heart medication. While spacing them out may help reduce the risk of interaction, it does not eliminate the potential for cumulative effects. It is still advisable to consult with your healthcare provider about the specific timing and dosage.

4. Monitoring Symptoms: If you decide to take both, closely monitor any symptoms such as unusual fatigue, muscle pain, or changes in heart rhythm. Report any concerning symptoms to your healthcare provider immediately.

5. Consult Your Doctor: Ultimately, the best course of action is to discuss this combination with your healthcare provider. They can provide personalized advice based on your medical history, current medications, and overall health status. They may also suggest alternative supplements or dietary changes that can support your heart health without the risk of interactions.


Conclusion:
In summary, while natto and red yeast rice may offer cardiovascular benefits, their interaction with heart medications can pose risks. It is crucial to consult with your healthcare provider before combining these supplements with your prescribed medication. They can help ensure that your treatment plan is safe and effective, taking into account your specific health needs and conditions. Always prioritize open communication with your healthcare team to manage your heart health effectively.

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