Can You Safely Take Natto Red Yeast and Fish Oil Together? - Nutrition

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Can these two dietary supplements be taken together?


Recently, an elder in my family purchased natto and red yeast rice, and has started taking them.
They are considering buying fish oil as well.
I would like to ask the doctor if it is safe to take these two supplements simultaneously.
I noticed that both have effects related to lowering blood pressure, cholesterol, and have anticoagulant properties.
I am concerned that taking too many similar supplements could lead to adverse effects.
Currently, the elder is only taking calcium supplements and natto and red yeast rice, with no other products or medications.
Thank you, doctor, for your assistance!

Niu, 20~29 year old female. Ask Date: 2021/03/21

Dr. Zhang Huangyu reply Nutrition


Hello, in response to your question, I would like to ask: Is the supplementation of such health products due to the elderly already having cardiovascular-related symptoms such as hypertension and hyperlipidemia? If so, I recommend that the elderly visit a hospital outpatient clinic for medical care and regular follow-ups.
Health supplements cannot target specific symptoms or treat diseases; improper use can indeed pose risks related to coagulation and other effects.
The suggested approach is to follow medical advice for regular medication, along with dietary treatment guided by a nutritionist (such as the DASH diet or Mediterranean diet).
Adjusting medications, diet, and lifestyle together is the best strategy.

Reply Date: 2021/03/21

More Info


When considering the simultaneous use of natto red yeast and fish oil, it's essential to understand the properties and potential interactions of these supplements. Both natto red yeast and fish oil are known for their cardiovascular benefits, including lowering blood pressure and cholesterol levels. However, combining them may raise concerns about their cumulative effects on blood thinning and lipid levels.

Natto red yeast contains monacolin K, which is a natural statin that can help lower cholesterol levels. Fish oil, on the other hand, is rich in omega-3 fatty acids, which are known to reduce triglycerides, lower blood pressure, and provide anti-inflammatory benefits. While both supplements can be beneficial for heart health, they also have blood-thinning properties. This means that taking them together could potentially enhance these effects, leading to an increased risk of bleeding, especially if the individual has underlying health conditions or is taking other medications that affect blood clotting.

Given that your family member is currently only taking calcium supplements along with natto red yeast, the addition of fish oil should be approached with caution. It is advisable to consult with a healthcare provider before starting fish oil, particularly to assess the individual's overall health, dietary habits, and any potential interactions with existing supplements.
If the healthcare provider gives the green light to take both supplements, it might be prudent to space out the consumption of natto red yeast and fish oil. For example, taking natto red yeast in the morning and fish oil in the evening can help minimize any potential interactions and allow the body to metabolize each supplement effectively.

In terms of dosage, it's crucial to adhere to the recommended amounts for both supplements. Overconsumption of either can lead to adverse effects. For instance, excessive intake of fish oil can lead to gastrointestinal issues, and high doses of natto red yeast can increase the risk of liver damage due to its statin-like effects. Regular monitoring of cholesterol levels and liver function tests may be warranted if both supplements are taken together.

Moreover, lifestyle factors such as diet and exercise play a significant role in cardiovascular health. Encouraging a balanced diet rich in fruits, vegetables, whole grains, and lean proteins, along with regular physical activity, can enhance the benefits of these supplements and contribute to overall heart health.

In summary, while it is possible to take natto red yeast and fish oil together, it is essential to do so under the guidance of a healthcare professional. Monitoring for any side effects and ensuring that the total intake of supplements does not exceed recommended levels is crucial for maintaining health and preventing complications.

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