Antihypertensive medications and red yeast rice?
Hello Director Huang: I would like to ask if it is okay to take the antihypertensive medication Acetec (4) once daily after breakfast, and in the evening, can I take a higher dosage (20000 FU/500 mg) of red yeast rice and natto?
lili, 30~39 year old female. Ask Date: 2012/03/17
Dr. Huang Shenggang reply Pharmacology
Hello Lili, regarding the consumption of red yeast rice and natto, may I ask if you have been taking them regularly? If you have, you can continue to take them.
If not, it is advisable to consult a physician for evaluation before starting.
Generally speaking, red yeast rice and natto are considered dietary supplements rather than medications, so as long as they are not taken in excess, they are safe to consume.
Reply Date: 2012/03/17
More Info
Combining Acetec (a medication used to lower blood pressure) with red yeast rice and natto can be a topic of concern for many patients managing hypertension. Acetec, which contains the active ingredient lisinopril, is an ACE inhibitor that helps relax blood vessels and lower blood pressure. On the other hand, red yeast rice is a traditional Chinese medicine that contains monacolin K, which is similar to the active ingredient in statin medications, and is often used to help manage cholesterol levels. Natto, a fermented soybean product, is rich in vitamin K2 and has been associated with various health benefits, including potential cardiovascular benefits.
From the information provided, it appears that the use of red yeast rice and natto alongside Acetec is generally considered safe, provided that the dosages are appropriate and monitored. However, it is crucial to consult with a healthcare provider before starting any new supplement, especially when on prescription medications. This is because while red yeast rice can help lower cholesterol, it may also have a mild blood pressure-lowering effect, which could potentially enhance the effects of Acetec, leading to an excessive drop in blood pressure.
Moreover, the interaction between these supplements and medications can vary based on individual health conditions, other medications being taken, and overall dietary habits. For instance, if a patient has underlying kidney issues or is on other antihypertensive medications, the combination might need to be adjusted or monitored more closely.
In terms of safety, red yeast rice is generally well-tolerated, but it can cause side effects similar to statins, such as muscle pain or liver enzyme elevation. Therefore, regular monitoring of liver function and muscle health is advisable for anyone taking red yeast rice, especially in conjunction with other medications.
Natto, while beneficial for its vitamin K2 content, can interact with anticoagulant medications like warfarin, but it is less likely to pose a risk when combined with blood pressure medications like Acetec. However, patients should be cautious about their vitamin K intake if they are on blood thinners, as it can affect coagulation.
In summary, while combining Acetec with red yeast rice and natto may be safe for many individuals, it is essential to have a thorough discussion with a healthcare provider. They can provide personalized advice based on the patient's complete medical history, current medications, and specific health goals. Regular monitoring of blood pressure, liver function, and overall health is crucial when managing hypertension and incorporating supplements into the treatment regimen.
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