Is Long-Term Use of Amoxicillin Safe for Children?

Q: Is Long-Term Use of Amoxicillin Safe for Children?

Hello： Amoxicillin has a broad spectrum of antibacterial activity, including Haemophilus pertussis, Staphylococcus, Streptococcus pneumoniae, as well as Gram-positive and Gram-negative bacteria. <br>This medication is administered orally and is not affected by gastric acid or oth

Is the use of antibiotics safe?

Hello, my daughter has been seeing a doctor for a cold for quite some time.
Upon researching, I found that the doctor prescribed a medication called AMOXICILLIN (500MG), which is an antibiotic.
Since this medication has been prescribed every time, I am concerned about the potential adverse effects of prolonged use (she has had about 5-6 consultations).
Additionally, I couldn't find any information on another medication called SOONMELT; I am unsure what it is.
The prescription for AMOXICILLIN (500MG) is for 0.84 tablets taken twice a day for three days (a total of 5 tablets for three days, taken twice a day).
Thank you for your response!

JEAN, 30~39 year old female. Ask Date: 2004/11/22

Dr. Hou Fangmin reply Pharmacology

Hello: Amoxicillin has a broad spectrum of antibacterial activity, including Haemophilus pertussis, Staphylococcus, Streptococcus pneumoniae, as well as Gram-positive and Gram-negative bacteria.
This medication is administered orally and is not affected by gastric acid or other foods, allowing for good absorption in the gastrointestinal tract and rapid distribution throughout body tissues.
Amoxicillin is excreted via the biliary and urinary tracts, making it particularly effective for infections of the biliary and urinary systems.
However, it is ineffective against infections caused by filterable viruses, molds, and fungi.

Indications: Amoxicillin is widely used, primarily for treating streptococcal infections.
For respiratory conditions, it is indicated for sinusitis, pharyngitis, otitis media, laryngitis, tonsillitis, acute and chronic bronchitis, bronchiectasis, and pneumonia.

Dosage for children under 20 kg is 20 mg to 40 mg/kg per day, divided into multiple doses, so the dosage should be adjusted based on your child's weight.
The duration of antibiotic treatment is determined by the physician.
Another medication, Soonmelt, is also an antibiotic, typically formulated as a syrup containing 31.25 mg of amoxicillin per cc, with a total of 25 mg of amoxicillin and 6.25 mg of clavulanic acid for anti-inflammatory and antibacterial effects.
The dosage for children aged 7-12 years is 10 ml three times a day, while for children aged 0-7 years, it is 5 ml three times a day.
The duration of treatment will be decided by the physician based on your symptoms.
Thank you for your question, goodbye.

Reply Date: 2004/11/22

More Info

The long-term use of amoxicillin in children raises valid concerns among parents, especially when it comes to potential side effects and the risk of antibiotic resistance. Amoxicillin is a broad-spectrum antibiotic that is commonly prescribed for various bacterial infections, including respiratory tract infections, ear infections, and sinusitis. While it is generally considered safe for children when prescribed by a healthcare provider, there are several factors to consider regarding its prolonged use.

Potential Negative Effects of Long-Term Amoxicillin Use
1. Antibiotic Resistance: One of the most significant concerns with the long-term use of antibiotics, including amoxicillin, is the development of antibiotic resistance. This occurs when bacteria evolve and become resistant to the effects of the antibiotic, making future infections harder to treat. This is particularly concerning in children, as they may require antibiotics for various infections throughout their lives.

2. Impact on Gut Flora: Antibiotics can disrupt the natural balance of bacteria in the gut. This disruption can lead to gastrointestinal issues such as diarrhea, nausea, and abdominal pain. In some cases, it can also result in opportunistic infections, such as Clostridium difficile, which can cause severe diarrhea and colitis.

3. Potential Allergic Reactions: Some children may develop an allergic reaction to amoxicillin, which can manifest as rashes, hives, or even more severe reactions like anaphylaxis. It's essential to monitor for any signs of an allergic reaction, especially with repeated courses of the medication.

4. Nutritional Absorption: Long-term antibiotic use may affect the absorption of certain nutrients, potentially leading to deficiencies. This is particularly important in growing children, as they require adequate nutrition for proper development.

Recommendations for Parents
1. Consult with Healthcare Providers: If your child has been prescribed amoxicillin multiple times, it is crucial to discuss this with your healthcare provider. They can evaluate the necessity of continued antibiotic therapy and consider alternative treatments if appropriate.

2. Consider Non-Antibiotic Treatments: For conditions that do not require antibiotics, such as viral infections, supportive care (hydration, rest, and over-the-counter medications for symptom relief) may be more appropriate. Discuss with your doctor the possibility of using non-antibiotic treatments for your child's symptoms.

3. Monitor for Side Effects: Keep an eye on your child for any side effects or unusual symptoms while they are on amoxicillin. If you notice anything concerning, contact your healthcare provider immediately.

4. Educate on Antibiotic Use: Teach your child the importance of using antibiotics responsibly. They should understand that antibiotics are not effective against viral infections and that they should only be taken when prescribed by a healthcare professional.

Regarding Soonmelt
As for the medication "Soonmelt," it appears to be a formulation that includes amoxicillin and possibly clavulanic acid, which is often used to enhance the effectiveness of amoxicillin against certain resistant bacteria. It is typically available in a syrup form, making it easier for children to take. If you have concerns about this medication, it is best to consult your healthcare provider for specific information regarding its use and any potential side effects.

Conclusion
In summary, while amoxicillin is generally safe for children when used as prescribed, long-term use should be approached with caution. Parents should maintain open communication with their healthcare providers to ensure that their child's treatment plan is appropriate and to explore alternative options when necessary. Monitoring for side effects and understanding the implications of antibiotic use are essential steps in safeguarding your child's health.

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