Cone Biopsy Results: What to Do After Abnormal Pap Smears? - Obstetrics and Gynecology

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Cervical conization


Hello Dr.
Lee,
I had a cone biopsy on February 2nd, and the report showed no residual disease, which was very reassuring at the time.
However, during my routine Pap smear on May 1st, an abnormality was detected again, with a grade of 10, up from 9 before the surgery.
I am confused as to why it increased by one grade.
The doctor performed a colposcopy and said he couldn't see anything abnormal, but he recommended a hysterectomy for safety reasons.
What should I do? I feel very helpless (I have one child and do not plan to have more).
Is it absolutely necessary to have the uterus removed?
Additionally, during my routine check on May 1st, an abnormality was found, but my HPV test was normal at 0.71, which is negative.
On May 10th, I went to the original biopsy hospital for a small biopsy, and the results were normal for the uterus, endocervix, and endometrium, with no specific changes noted.
Can you please explain why this is happening? Thank you.

ha, 30~39 year old female. Ask Date: 2007/05/18

Dr. Li Guanghan reply Obstetrics and Gynecology


Hello: Your questions have been answered.
If you have any further inquiries, please bring all your smear tests, biopsy results, and HPV examination reports to our obstetrics and gynecology outpatient clinic for consultation.
Thank you! Hsinchu Hospital, Department of Obstetrics and Gynecology.

Reply Date: 2007/05/18

More Info


Understanding the results of a cone biopsy and the subsequent management after abnormal Pap smears can be quite complex and often emotionally taxing. It's essential to break down the findings and recommendations to provide clarity and guidance.

Firstly, a cone biopsy is a procedure where a cone-shaped piece of tissue is removed from the cervix for examination. This is typically done when there are abnormal cells detected in a Pap smear, which can indicate precancerous changes or cervical cancer. The fact that your initial cone biopsy report indicated "no residual" abnormal cells is indeed reassuring. However, the subsequent Pap smear showing an increase in abnormality from a grade of 9 to 10 is concerning and warrants further investigation.

The grading system for cervical cytology can vary, but generally, a higher grade indicates a greater degree of abnormality. The increase in grade could be due to several factors, including the possibility of sampling error, where the biopsy may not have captured all areas of abnormality, or the presence of new lesions that developed after the initial biopsy. It’s important to note that the HPV test being negative is a positive sign, as high-risk HPV types are often associated with the development of cervical cancer.

Your doctor’s recommendation for a hysterectomy (removal of the uterus) is likely based on the desire to ensure that any potential precancerous changes are completely addressed. Given that you have one child and do not plan to have more children, this may be a more straightforward option for you. A hysterectomy can provide peace of mind by eliminating the risk of cervical cancer altogether. However, it is also a significant surgical procedure with its own risks and implications, including hormonal changes if the ovaries are removed.

If you are feeling uncertain about this recommendation, it is entirely reasonable to seek a second opinion. You might also consider discussing the following with your healthcare provider:
1. Clarification of Findings: Ask for a detailed explanation of the Pap smear results and how they correlate with your previous biopsy. Understanding why there is a discrepancy can help you make an informed decision.

2. Alternative Management Options: Inquire about other management strategies that may be available, such as more frequent monitoring with Pap smears and HPV testing, or other less invasive procedures that could be considered before opting for a hysterectomy.

3. Risks and Benefits: Discuss the risks and benefits of a hysterectomy versus continued monitoring. Understanding the potential outcomes of each option can help you weigh your choices more effectively.

4. Emotional Support: It’s normal to feel overwhelmed in this situation. Consider speaking with a counselor or joining a support group for women facing similar health issues. Emotional support can be invaluable during this time.

In conclusion, while the recommendation for a hysterectomy may be a precautionary measure, it is crucial to ensure that you feel comfortable and informed about your decision. Engaging in open dialogue with your healthcare provider and seeking additional opinions can empower you to make the best choice for your health and well-being. Remember, your health decisions should align with your personal circumstances, values, and future family planning considerations.

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