Beta-Carotene: Dosage, Risks, and Recommendations - Nutrition

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Beta-carotene


Hello, Doctor! I have a few questions to ask:
1.
The beta-carotene supplements on the market are typically 25,000 IU per capsule, which is 500% of the daily requirement for the human body.
If a person is already obtaining beta-carotene and vitamin A from their diet, how often should they take one of these high-dose beta-carotene capsules? And if someone is not getting any beta-carotene or vitamin A from their diet, how often should they take one capsule?
2.
It is said that beta-carotene is not suitable for smokers.
If a family member smokes and another person is exposed to secondhand smoke, is it still appropriate for them to take beta-carotene?
3.
Is it true that individuals with diabetes cannot convert beta-carotene to vitamin A, and that taking vitamin A can lead to decreased bone density? If a person with diabetes is taking vitamin A, should they take it alongside calcium and magnesium supplements?
Thank you for your guidance!

Ms. Li, 30~39 year old female. Ask Date: 2017/08/05

Dr. Cai Xiuwen reply Nutrition


Hello! Excessive intake of vitamin A can be toxic, whereas beta-carotene does not exhibit such toxicity.
It has been mentioned in some articles that the half-life of vitamin A in the body is approximately 128 to 154 days, thus the necessity for additional supplementation of vitamin A remains to be discussed.
Several studies have confirmed a relationship between beta-carotene and the incidence and mortality of lung cancer, suggesting that regardless of smoking or secondhand smoke exposure, it is advisable to consume natural vitamins from deep green and deep red fruits and vegetables for safer supplementation.
There have been no studies linking vitamin A supplementation to osteoporosis, so additional mineral supplementation should not be pursued.
It is still recommended to obtain nutrients from a variety of natural foods as the best source.
Wishing you peace and health.
This message is from Dietitian Tsai Hsiu-Wen at Nantou Hospital, Ministry of Health and Welfare.

Reply Date: 2017/08/05

More Info


Beta-carotene is a precursor to vitamin A and is found in various fruits and vegetables, particularly those that are orange or yellow in color, such as carrots, sweet potatoes, and pumpkins. It is important to understand its dosage, risks, and recommendations, especially for individuals with specific health concerns.

1. Dosage Recommendations: The typical dosage for beta-carotene supplements can vary widely. A common supplement dose is indeed around 25,000 IU, which is significantly higher than the recommended dietary allowance (RDA) for vitamin A. If you are consuming a diet rich in beta-carotene and vitamin A, it may not be necessary to take such high doses frequently. For individuals who consume adequate amounts of beta-carotene through their diet, taking a supplement every few days or even weekly may be sufficient. Conversely, if your diet lacks beta-carotene and vitamin A, you might consider taking the supplement more regularly, perhaps every other day, but it is advisable to consult with a healthcare provider for personalized recommendations.

2. Smoking and Secondhand Smoke: It is well-documented that beta-carotene supplementation may pose risks for smokers. Studies have shown that high doses of beta-carotene can increase the risk of lung cancer in smokers. If a person is exposed to secondhand smoke, the risks are less clear, but caution is still warranted. It is generally recommended that individuals who smoke or are regularly exposed to secondhand smoke avoid high-dose beta-carotene supplements. If your family member smokes, it would be prudent to discuss the use of beta-carotene with a healthcare professional before proceeding.

3. Diabetes and Vitamin A Conversion: There is some evidence suggesting that individuals with diabetes may have impaired conversion of beta-carotene to vitamin A. However, this does not mean that all diabetics should avoid beta-carotene. Instead, they should be monitored for their vitamin A levels and overall health. Regarding vitamin A supplementation, it is true that excessive intake can lead to adverse effects, including potential impacts on bone density. Therefore, if a diabetic individual is taking vitamin A supplements, it may be beneficial to take them alongside calcium and magnesium to support bone health. However, this should be done under medical supervision to ensure that the dosages are appropriate and safe.

In summary, while beta-carotene can be a beneficial supplement, its use should be tailored to individual dietary intake, health status, and lifestyle factors such as smoking. It is always best to consult with a healthcare provider before starting any new supplement regimen, especially for individuals with specific health conditions like diabetes or those who are exposed to smoking. Regular monitoring and adjustments based on individual needs and responses to supplementation are key to ensuring safety and efficacy.

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