Rheumatoid Arthritis: Symptoms, Diagnosis, and Treatment Options - Rehabilitation

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Rheumatoid Arthritis


Last year, I experienced unexplained pain in the joint near the nail of my right big toe, which persisted for some time.
Later, I noticed that bending it caused pain, and the joint became red and painful.
After visiting an orthopedic specialist, I underwent laser treatment, but there was little improvement.
I then sought a second opinion at another hospital, where the doctor asked if I experienced stiffness in other joints.
I mentioned that my fingers felt stiff.
He suggested that there might be a multi-joint issue and recommended that I undergo tests for autoimmune rheumatic diseases.
However, the blood test results came back normal, indicating that this might not be the problem.

I returned to the original orthopedic specialist, who suggested a corticosteroid injection in the joint.
After receiving the injection, I felt some improvement, as the pain during bending was less intense, but the joint appeared red and dark.
Recently, the joint has started to bend and hurt again, and I have also begun to experience pain in the sunken area below my left ankle while walking; now, even at rest, it hurts.
I underwent ultrasound therapy, but there was no improvement.
Additionally, my right pinky finger has similar pain when pressure is applied to the joint near the nail, and bending it also causes pain.
Not long after, my left index finger developed the same issue near the nail joint.
Both hands are experiencing stiffness, and various unexplained symptoms keep appearing, even though I haven't sustained any injuries.

I would like to ask if I need to undergo another autoimmune blood test.
Could the results vary over time? Besides the suspected condition, are there other potential diseases that could be considered?

pony, 40~49 year old female. Ask Date: 2023/10/23

Dr. Lin Ruixiang reply Rehabilitation


Hello: Based on your description, this is not a localized issue but rather a systemic problem.
It is advisable to initially investigate the symptoms from a rheumatological and immunological perspective.
Hualien Hospital, Ministry of Health and Welfare, cares about your health.

Reply Date: 2023/10/23

More Info


Rheumatoid arthritis (RA) is a chronic inflammatory disorder that primarily affects the joints, but it can also have systemic effects on other organs. Understanding its symptoms, diagnosis, and treatment options is crucial for effective management.

Symptoms of Rheumatoid Arthritis
RA typically presents with a variety of symptoms, including:
1. Joint Pain and Swelling: The most common symptom is pain and swelling in the joints, particularly in the hands, wrists, and feet. In your case, the pain in your toe and fingers aligns with typical RA symptoms.


2. Morning Stiffness: Many patients experience stiffness in the joints, especially in the morning or after periods of inactivity. This stiffness can last for more than 30 minutes, which is a key distinguishing factor from osteoarthritis.

3. Fatigue and Malaise: Patients often report feeling tired and unwell, which can be debilitating.

4. Symmetrical Joint Involvement: RA usually affects joints on both sides of the body equally, which is something to consider as you experience symptoms in both hands and feet.

5. Systemic Symptoms: RA can also lead to systemic issues such as fever, weight loss, and anemia.


Diagnosis of Rheumatoid Arthritis
Diagnosing RA involves a combination of clinical evaluation and laboratory tests:
1. Clinical Examination: A rheumatologist will assess your symptoms, joint involvement, and any physical signs of inflammation.

2. Blood Tests: While your initial blood tests came back normal, it is important to note that RA can sometimes be seronegative, meaning that not all patients will test positive for rheumatoid factor (RF) or anti-citrullinated protein antibodies (anti-CCP).
3. Imaging Studies: X-rays or ultrasounds can help assess joint damage and inflammation.

4. Follow-Up Tests: Given your ongoing symptoms, it may be prudent to repeat blood tests to check for any changes over time, as autoimmune diseases can evolve.


Treatment Options for Rheumatoid Arthritis
Treatment for RA is multifaceted and typically includes:
1. Medications:
- Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): These can help reduce pain and inflammation.

- Corticosteroids: As you have already experienced, corticosteroids can provide quick relief from inflammation but are not a long-term solution due to potential side effects.

- Disease-Modifying Antirheumatic Drugs (DMARDs): Medications like methotrexate are commonly used to slow disease progression and prevent joint damage.

- Biologic Agents: If traditional DMARDs are ineffective, biologics may be considered. These target specific pathways in the inflammatory process.

2. Physical Therapy: Engaging in physical therapy can help maintain joint function and reduce stiffness.

3. Lifestyle Modifications: Regular exercise, a balanced diet, and weight management can significantly impact overall health and joint function.

4. Monitoring and Follow-Up: Regular follow-ups with your rheumatologist are essential to monitor disease progression and adjust treatment as necessary.


Other Considerations
Given your symptoms and the complexity of your case, it is important to consider other potential diagnoses, such as:
- Psoriatic Arthritis: If you have any skin symptoms or a family history of psoriasis.

- Gout: Particularly if you have a history of elevated uric acid levels.

- Other Autoimmune Conditions: Conditions like lupus or spondyloarthritis could also present with similar symptoms.


Conclusion
In summary, your symptoms warrant further investigation, including possibly repeating immune tests and considering other diagnoses. It is essential to maintain open communication with your healthcare providers and advocate for your health. If your symptoms persist or worsen, seeking a second opinion or further evaluation from a rheumatologist may be beneficial. Early and effective management of RA can significantly improve quality of life and prevent long-term joint damage.

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