Is Natto Extract Safe for Patients with High Blood Pressure and Brain Hemorrhage?

Q: Is Natto Extract Safe for Patients with High Blood Pressure and Brain Hemorrhage?

Dear Xiaofen, Hello. Regarding long-term care： 1. When feeding via a nasogastric tube, it is important to monitor for any residual food during aspiration. 2. If the endotracheal tube has been removed, it is necessary to perform suctioning and reposition the p

Single-component natto extract dietary supplement?

Hello Dr.
Chang,
I have a few questions to ask you.
My mother-in-law has a history of hypertension and has been on medication for a long time.
On January 10th, around 7:30 PM, while dining at my sister-in-law's house, she suddenly experienced weakness on her left side.
When my sister-in-law asked if she felt unwell, she replied that she had taken her medication.
Around 8:30 PM, my family and I accompanied her to Hsinchu Hospital for treatment.
After examination, the doctor ordered X-rays and a CT scan of the brain, which revealed three areas of bleeding, approximately 1.5 cm each.
The doctor informed us that she needed to be admitted to the surgical intensive care unit for observation, so we went home.

However, at 4 AM, the hospital called to inform us that her Glasgow Coma Scale score had dropped to 8, and if not addressed, she would not have another chance.
Consequently, she was taken to the operating room for drainage at 5 AM.
Post-surgery, she regained consciousness within about three days and was able to respond clearly to finger movements.
Since then, she has been in a state of drowsiness.
During visiting hours, family members have patiently assisted her with rehabilitation.
Recently, her condition seems to have improved slightly, and the brain drainage tube has been removed.
The doctor mentioned that the bleeding in the brain may be reabsorbed on its own; if not, she would need to undergo another procedure to drain it into the abdominal cavity.
She is still intubated and receiving nutrition through a nasogastric tube.
On January 28th, my brother-in-law heard from a friend about a Japanese product, natto extract, which is said to be beneficial for vascular absorption and can help with clearing blood vessels and reabsorbing the bleeding.
However, since my mother-in-law is still in the intensive care unit, I would like to know if it is appropriate for her to take natto extract at this time.
If she is later transferred to a regular ward, can she take it then? What conditions would make it more suitable for someone to take it? What should we pay attention to for long-term care?

Xiao Fen, 20~29 year old female. Ask Date: 2010/02/08

Dr. Shi Guimei reply Nutrition

Dear Xiaofen,
Hello.
Regarding long-term care:
1.
When feeding via a nasogastric tube, it is important to monitor for any residual food during aspiration.
2.
If the endotracheal tube has been removed, it is necessary to perform suctioning and reposition the patient at regular intervals to prevent pneumonia and pressure ulcers.
3.
Bedside rehabilitation is preferable to avoid limb contractures.

Additionally, nattokinase does not have any efficacy in clearing blood vessels or in the absorption of bleeding.
When administering nutrition via a nasogastric tube, it is best to provide a formula specifically designed for tube feeding.
Wishing you safety and health.
Sincerely,
Dr.
Zhang Yuanyi, Attending Physician, Department of Neurosurgery, Taoyuan General Hospital, Ministry of Health and Welfare
Dietitian Shi Guimei, Director of Nutrition Department

Reply Date: 2010/02/08

More Info

Natto extract, particularly its active component, nattokinase, has gained attention for its potential health benefits, particularly in cardiovascular health. However, when considering its use in patients with high blood pressure and a history of brain hemorrhage, caution is warranted.

Nattokinase is an enzyme derived from fermented soybeans and is believed to have fibrinolytic properties, meaning it may help dissolve blood clots. While this could theoretically be beneficial for vascular health, it is crucial to understand that the use of nattokinase in patients with a history of brain hemorrhage or significant hypertension poses potential risks.

1. Risk of Bleeding: Given that your mother-in-law has experienced a brain hemorrhage, introducing any substance that has blood-thinning properties could increase the risk of further bleeding. Nattokinase may enhance the effects of anticoagulant medications or other blood-thinning agents, leading to complications. In patients with a history of hemorrhagic stroke, the priority is to stabilize their condition and prevent any further bleeding.

2. Blood Pressure Considerations: While some studies suggest that nattokinase may help lower blood pressure, the effects can vary significantly among individuals. For someone with chronic hypertension, especially if they are already on antihypertensive medications, introducing nattokinase could lead to unpredictable changes in blood pressure. This is particularly concerning in a patient who is already experiencing fluctuations in blood pressure due to their medical condition.

3. Current Medical Status: Your mother-in-law is currently in a critical recovery phase after a significant medical event. The focus should be on her recovery and rehabilitation. Introducing new supplements or medications during this time could complicate her treatment plan and recovery process. It is essential to consult with her healthcare team before considering any new treatments, including nattokinase.

4. Long-term Care Considerations: In terms of long-term care, it is vital to monitor her blood pressure closely, ensure she adheres to her prescribed medications, and maintain a healthy lifestyle. This includes a balanced diet low in sodium, regular physical activity as tolerated, and routine follow-up appointments with her healthcare provider. Additionally, any new supplements or medications should be discussed with her doctor to ensure they do not interfere with her current treatment plan.

5. Consultation with Healthcare Providers: Before making any decisions regarding the use of nattokinase or any other supplement, it is crucial to have a detailed discussion with her neurologist or primary care physician. They can provide personalized advice based on her medical history, current medications, and overall health status.

In summary, while nattokinase may have potential benefits for some individuals, its use in patients with high blood pressure and a history of brain hemorrhage should be approached with caution. The risks of bleeding, potential interactions with medications, and the current medical condition of your mother-in-law necessitate a thorough evaluation by her healthcare team before considering any new treatment options. Prioritizing her recovery and ensuring a stable medical condition should be the primary focus at this time.

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