Top Antioxidant Supplements to Avoid for Cancer Patients - Nutrition

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What nutritional supplements and health products contain antioxidants?


I just saw a news article mentioning that the research author Martin Bego cautions cancer patients and high-risk groups to avoid taking dietary supplements and health products containing antioxidants, as this may hinder health efforts and potentially promote the spread and metastasis of cancer cells.
I would like to ask a nutritionist which dietary supplements and health products contain antioxidants.
Could you provide some examples?

Xiao Xiao, 20~29 year old female. Ask Date: 2015/10/17

Dr. Huang Yuru reply Nutrition


Hello: Dietary supplements are classified as general food products, but they differ from regular foods in that they contain certain ingredients that can be effective for human health or disease prevention, provided that their effects are supported by scientific research and clinical evidence.
While dietary supplements can have some physiological effects on the body, these effects are generally mild and tend to have fewer side effects.
Unlike medications, which are taken to treat illnesses and should be discontinued once recovery occurs, dietary supplements are used more for maintenance and prevention.

Common types of dietary supplements available on the market include: 1.
Liquid forms, such as chicken essence, clam essence, and health drinks; 2.
Powder forms, such as lecithin and spirulina; 3.
Capsules, such as vitamin E and beta-carotene; 4.
Tablets, such as calcium tablets and vitamin C.
Antioxidant supplements, including vitamins A, C, E, beta-carotene, and selenium, also fall under the category of dietary supplements.
Thank you for your inquiry.

Reply Date: 2015/10/17

More Info


When it comes to cancer patients or those at high risk for cancer, the use of antioxidant supplements has become a topic of considerable debate. Recent studies, including those referenced by researchers like Martin Bego, suggest that high doses of antioxidants may interfere with conventional cancer treatments and potentially promote tumor growth. This is particularly concerning for patients undergoing chemotherapy or radiation therapy, as antioxidants can neutralize the oxidative stress that these treatments rely on to kill cancer cells.

Antioxidant supplements are widely available and can be found in various forms, including vitamins, minerals, and herbal extracts. Some common examples of antioxidant supplements include:
1. Vitamin C (Ascorbic Acid): Often taken to boost the immune system, high doses of vitamin C can act as an antioxidant but may also interfere with certain cancer therapies.

2. Vitamin E: This fat-soluble vitamin is known for its antioxidant properties. However, some studies have suggested that it may protect cancer cells from the effects of chemotherapy.

3. Beta-Carotene: Found in carrots and other vegetables, beta-carotene is a precursor to vitamin A. Some studies have indicated that high doses of beta-carotene may increase the risk of lung cancer in smokers.

4. Selenium: While selenium is an essential mineral with antioxidant properties, excessive supplementation has been linked to adverse effects, including increased risk of certain cancers.

5. Coenzyme Q10 (CoQ10): This antioxidant is often marketed for its supposed health benefits, but there is limited evidence regarding its efficacy in cancer treatment.

6. Curcumin: Derived from turmeric, curcumin has been touted for its anti-inflammatory and antioxidant properties. However, its effects on cancer treatment are still under investigation.

7. Green Tea Extract: Rich in polyphenols, particularly epigallocatechin gallate (EGCG), green tea extract is often consumed for its health benefits. However, its interaction with cancer therapies is still being studied.

8. Resveratrol: Found in red wine and grapes, resveratrol is another antioxidant that has garnered attention for its potential health benefits, but its role in cancer treatment remains unclear.

The concern with these supplements arises from the fact that while antioxidants can be beneficial in normal physiological conditions, they may not be advantageous for cancer patients. The rationale is that cancer cells often thrive in an oxidative environment, and by neutralizing free radicals, antioxidants could inadvertently provide a more favorable environment for tumor growth.

Moreover, the use of high-dose antioxidant supplements can lead to potential interactions with chemotherapy drugs, reducing their effectiveness. For instance, some studies have shown that antioxidants can protect cancer cells from the cytotoxic effects of chemotherapy, leading to treatment resistance.

Given these considerations, it is crucial for cancer patients to consult with their healthcare providers before starting any new supplement regimen. Oncologists and registered dietitians can provide personalized advice based on the patient's specific treatment plan and health status.
In conclusion, while antioxidants play a vital role in health, their use as supplements in cancer patients should be approached with caution. It is essential to prioritize a balanced diet rich in whole foods, which naturally contain antioxidants, rather than relying on concentrated supplements. Whole foods provide a complex array of nutrients that work synergistically, offering protective benefits without the risks associated with high-dose supplements. Always discuss any dietary changes or supplement use with your healthcare team to ensure the best outcomes in cancer treatment.

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