Can Patients with Favism Safely Consume Fish Oil and Vitamins? - Pharmacology

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Can individuals with Favism consume fish oil and vitamins?


As a patient with G6PD deficiency, can I take Youkang Concentrated Fish Oil EPA Softgels? Will taking Youkang Concentrated Fish Oil EPA Softgels have any effects? What is the recommended daily dosage of fish oil for an individual? Can individuals with G6PD deficiency take Centrum multivitamins? Additionally, aside from fava beans, camphor, and medications like aspirin, sulfonamides, antimalarials, and topical gentian violet that can trigger hemolytic reactions, what other substances should be avoided? Thank you for addressing these questions.

Xiao Yan, 20~29 year old female. Ask Date: 2017/11/08

Dr. Liao Lingmei reply Pharmacology


Hello: 1.
There is no confirmed evidence of contraindications for fish oil consumption in individuals with G6PD deficiency (Glucose-6-Phosphate Dehydrogenase Deficiency).
2.
There is also no relevant information regarding the effects of fish oil on individuals with G6PD deficiency.
3.
The dosage of fish oil varies depending on the intended purpose; for reducing triglycerides, the effective component Icosapent Ethyl should be taken at a daily dose of 4g, while other purposes are experimental and lack specific dosages.
4.
Individuals with G6PD deficiency can take Centrum multivitamins; please follow the recommended dosage on the bottle.
5.
Individuals with G6PD deficiency should inform their physician during consultations, as caution is advised regarding medications, especially since there are several sulfonamide drugs.
Please confirm with a pharmacist before taking any medication.
Wishing you health and happiness!

Reply Date: 2017/11/08

More Info


Favism, or G6PD deficiency, is a genetic condition that affects the enzyme glucose-6-phosphate dehydrogenase, which plays a crucial role in protecting red blood cells from oxidative stress. Individuals with this condition can experience hemolytic anemia when exposed to certain triggers, including specific foods and medications.
Regarding the consumption of fish oil and vitamins for individuals with favism, current medical literature does not indicate any specific contraindications for fish oil. Fish oil, which is rich in omega-3 fatty acids (EPA and DHA), has been shown to have various health benefits, including anti-inflammatory properties and potential cardiovascular benefits. However, it is essential to consult with a healthcare provider before starting any new supplement, especially for individuals with underlying health conditions like favism.

When it comes to the specific product you mentioned, "悠康-細旨濃縮魚油EPA軟膠囊," there is no documented evidence suggesting that it poses a risk for individuals with G6PD deficiency. However, it is crucial to monitor for any adverse reactions when introducing new supplements into the diet. The recommended dosage of fish oil can vary based on individual health goals, but for general health benefits, a common recommendation is around 1,000 mg of combined EPA and DHA per day. For specific health conditions, higher doses may be recommended, but this should always be discussed with a healthcare professional.

As for multivitamins, individuals with favism can generally take a multivitamin like "善存綜合維他命," but again, it is essential to adhere to the recommended dosage on the label. Some vitamins, particularly vitamin C, can potentially increase oxidative stress, so it is advisable to consult with a healthcare provider regarding the appropriate type and amount of vitamins to take.

In addition to fava beans, individuals with favism should avoid certain medications and substances that can trigger hemolysis. These include:
1. Certain antibiotics: Sulfonamides and nitrofurantoin are known to cause hemolytic reactions in G6PD-deficient individuals.

2. Antimalarials: Drugs like primaquine can also trigger hemolysis.

3. Certain analgesics: Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) should be used cautiously.

4. Mothballs: Products containing naphthalene can cause oxidative stress and should be avoided.

5. Certain foods: Besides fava beans, other legumes may also pose a risk, although they are generally less harmful.

In conclusion, while fish oil and multivitamins can be safely consumed by individuals with favism, it is crucial to consult with a healthcare provider before starting any new supplement regimen. Monitoring for any adverse reactions is essential, and individuals should remain vigilant about avoiding known triggers that can lead to hemolytic episodes. Regular check-ups and open communication with healthcare providers can help manage favism effectively and maintain overall health.

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