Oxalic Acid: Its Impact on Calcium and Nutrient Absorption - Nutrition

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Oxalic acid?


1.
Are oxalic acid and folic acid the same? Last time I asked you a question, you replied that calcium carbonate requires stomach acid for absorption.
If I take calcium supplements more than half an hour after a meal, will it be unable to absorb?
2.
Besides not being able to take calcium supplements with spinach, do fruits such as citrus, oranges, tomatoes, pineapples, and papayas have any conflicts with calcium absorption? Thank you!

Wei, 30~39 year old female. Ask Date: 2004/04/15

Dr. Shi Guimei reply Nutrition


Hello! 1.
Oxalic acid is different from folic acid; folic acid is a vitamin that is essential for the human body, while oxalic acid, also known as ethanedioic acid, readily binds with calcium to form precipitates.
If calcium supplements are taken more than half an hour after a meal, it will not be completely unabsorbed, but the absorption rate will be reduced.
2.
Fruits rich in vitamin C can enhance calcium absorption, so the fruits mentioned in your question, which are high in vitamin C, can increase the absorption rate of calcium.
Sincerely, Dietitian Shih Kuei-Mei, Director of the Nutrition Department, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2004/04/15

More Info


Oxalic acid, commonly found in various foods, plays a significant role in the absorption of calcium and other nutrients in the body. To address your questions, let's first clarify the relationship between oxalic acid and calcium, and then explore its interactions with other nutrients.

1. Oxalic Acid vs. Folic Acid: Oxalic acid and folic acid are not the same. Oxalic acid is an organic compound that can bind with calcium to form calcium oxalate, which is insoluble and can contribute to the formation of kidney stones. Folic acid, on the other hand, is a B-vitamin (B9) essential for DNA synthesis and repair, as well as for the production of red blood cells. While both compounds are found in plant foods, their functions and effects on the body are quite different.

2. Calcium Absorption and Stomach Acid: It is true that calcium carbonate requires stomach acid for optimal absorption. If calcium supplements are taken without adequate stomach acid, such as after a prolonged period of fasting or if the stomach is not producing enough acid, the absorption may be impaired. Taking calcium supplements more than 30 minutes after a meal may reduce their absorption efficiency, especially if the meal did not stimulate sufficient gastric acid production.

3. Interactions with Other Foods: When it comes to food interactions, it is essential to consider the presence of oxalic acid in certain foods. For instance, spinach, rhubarb, and beet greens are high in oxalates and can inhibit calcium absorption when consumed together with calcium-rich foods or supplements. However, the fruits you mentioned—such as oranges, tomatoes, pineapples, and papayas—do not contain significant amounts of oxalic acid and are generally safe to consume with calcium. In fact, citrus fruits like oranges can enhance calcium absorption due to their vitamin C content, which may help improve the bioavailability of certain minerals.

4. General Recommendations: For individuals concerned about calcium absorption, especially those at risk for kidney stones or osteoporosis, it is advisable to limit the intake of high-oxalate foods when consuming calcium-rich foods or supplements. Drinking plenty of water can also help dilute the concentration of oxalates in the urine, potentially reducing the risk of stone formation. Additionally, balancing your diet with a variety of foods can help ensure adequate nutrient intake without excessive reliance on any single food source.

5. Conclusion: Understanding the role of oxalic acid in nutrient absorption is crucial for maintaining optimal health. While it can inhibit calcium absorption when consumed in large amounts, particularly in conjunction with calcium-rich foods, it is also important to recognize that not all foods containing oxalic acid will have the same impact. A balanced diet that includes a variety of fruits, vegetables, and adequate hydration can help mitigate potential negative effects while promoting overall nutrient absorption.

In summary, while oxalic acid can impact calcium absorption, its effects can be managed through dietary choices and timing. If you have specific health concerns or dietary restrictions, consulting with a healthcare professional or a registered dietitian can provide personalized guidance tailored to your needs.

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